Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Plaque Psoriasis, Psoriatic Arthritis, or Behcet’s Disease |
Dose: Tablet – 10 mg Frequency: once daily in morning Duration: Day 1 Note: Titrate to the recommended dose of 30 mg twice daily to reduce risk of gastrointestinal symptoms. |
|
Indication: Plaque Psoriasis, Psoriatic Arthritis, or Behcet’s Disease |
Dose: Tablet – 10 mg Frequency: twice daily (10 mg in morning and 10 mg in evening) Duration: Day 2 Note: Titrate to the recommended dose of 30 mg twice daily to reduce risk of gastrointestinal symptoms. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Plaque Psoriasis Age: 6 years of age and older |
Dose: Form – 10 mg Frequency: once daily in the morning Duration: Day 1 |
|
Indication: Plaque Psoriasis Age: 6 years of age and older |
Dose: Form – 10 mg Frequency: twice daily (10 mg in morning and 10 mg in evening) Duration: Day 2 |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult Condition: Mild-to-moderate renal impairment |
Dose: – Note: No dosage adjustment required |
|
Age: Adult Condition: Severe renal impairment (Creatinine Clearance less than 30 mL/min) |
Dose: – 10 mg Frequency: Morning Duration: Day 1 to Day 3 Note: For initial dosage titration, skip afternoon doses |
Administration
- Can take with or without food
- Start with lower dose
Side Effect
- Diarrhea (7.7-9.3%)
- Nausea (7.4-8.9%)
- Headache (4.8-5.9%)
- Upper respiratory tract infection (URTI) (0.6-3.9%)
- Vomiting (0.8-3.2%)
- Nasopharyngitis (0.2-2.6%)
- Upper abdominal pain (0.6-2%)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Strong CYP inducers (e.g. rifampin, carbamazepine, phenobarbital phenytoin)
|
May result in a loss of efficacy; coadministration not recommended
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Drug Hypersensitivity
|
Risk of allergic reaction
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at cool & dry place, protected from light & moisture. Keep the medicine out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.