Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is a local anesthetic used in surgeries and medical procedures. It works by blocking signal transmission in nerves, causing numbness.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Hospital use only • Given by healthcare provider • Requires monitoring • Medical supervision

Question 3

When should this medicine not be used?

Accepted Answer

• In liver/heart/breathing problems

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Use only under medical supervision • Tell doctor if you have liver, heart, or breathing problems • Be ready for emergency treatment • Use lower dose in elderly or weak patients

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• No specific pregnancy precautions noted

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Use only under medical supervision • Tell doctor if you have liver, heart, or breathing problems • Be ready for emergency treatment • Use lower dose in elderly or weak patients

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Reduce doses in children based on age and weight • Elderly may need lower doses

Question 8

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For once-daily dosing: If you remember on the same day, take the dose. • For twice-daily dosing: If more than 6 hours until your next dose, take the missed dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Symptoms: CNS toxicity, seizures, cardiac arrest. • Treatment: Airway support, anticonvulsants.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Numbness, dizziness, confusion, anxiety, tremors • What to do: Use under medical supervision, report irregular heartbeat; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is Locaine 2% used for?

Accepted Answer

Locaine 2% (Lidocaine (Lignocaine) Hydrochloride) is a pharmaceutical medicine manufactured by Aristopharma Limited in Bangladesh. It is primarily prescribed for Epidural Anesthesia, Haemorrhoids (Piles), Perianal Pain & Itching, Peripheral Nerve Block, Pupil Dilatation, Regional Anesthesia, Spinal Anesthesia, Surface Anesthesia, Sympathetic Nerve Block, Ventricular Arrhythmia, Ventricular Fibrillation or Ventricular Tachycardia.

Question 12

What is the active generic component of Locaine?

Accepted Answer

The active ingredient in Locaine is Lidocaine (Lignocaine) Hydrochloride.

Question 13

What is the retail price of Locaine 2% in Bangladesh?

Accepted Answer

The official retail price of Locaine 2% (Injection) is ৳28.74 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 14

What is the recommended dosage for Locaine?

Accepted Answer

Standard adult dosage: Intravenous – 1-1.5 mg/kg (slow intravenous bolus over 2-3 minutes). Pediatric dosage: Bolus – 0.5-1 mg/kg. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 15

Is Locaine safe during pregnancy and breastfeeding?

Accepted Answer

Locaine is classified under Pregnancy Category "B". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 16

What are the common side effects of Locaine?

Accepted Answer

**Common**; Cardiovascular Hypotension; Dermatologic Edema; erythema at injection site; petechiae; skin irritation;Gastrointestinal Constipation; Nausea; vomiting;Neurologic Confusion; dizziness; headache; paresthesia; s

Clinical Information	Administration Information
Indication: Ventricular Arrhythmias	Dose: Intravenous – 1-1.5 mg/kg Frequency: slow intravenous bolus over 2-3 minutes Note: May repeat doses of 0.5-0.75 mg/kg in 5-10 minutes up to 3 mg/kg total. Hepatic impairment: Dosage reduction may be needed.
Indication: Ventricular Arrhythmias	Dose: Intravenous – 1-4 mg/min Frequency: continuous infusion Note: Hepatic impairment: Dosage reduction may be needed.

Clinical Information	Administration Information
Indication: Ventricular Arrhythmias	Dose: Bolus – 0.5-1 mg/kg Note: Intravenous/Intraosseous/Endotracheal; not to exceed 100 mg; follow with continuous infusion; if delay between bolus and start of infusion is greater than 15 minutes, administer a second bolus every 5-10 minutes to 5 mg/kg
Indication: Ventricular Arrhythmias	Dose: Continuous infusion – 20-50 mcg/kg/min Note: Intravenous

Drug Name	Risk Factors
Cimetidine, Propranolol	May increase serum levels
Beta-blockers (Propranolol, Metoprolol, Atenolol, Bisoprolol, Carvedilol, Nadolol, Timolol, Sotalol), Other Antiarrhythmics (Amiodarone, Flecainide, Propafenone, Quinidine, Disopyramide, Procainamide)	Increased risk of cardiac depression

Disease Name	Risk Factors
Hypovolaemia	Risk of cardiovascular collapse
Heart block	Can worsen conduction problems

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources