Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Short-term management of haemorrhage
Age: Adult
Dose: Oral – 1-1.5 g or 15-25 mg/kg
Frequency: twice daily or three times daily
Indication: Management of hereditary angioedema
Age: Adult
Dose: Oral – 1-1.5 g
Frequency: twice daily or three times daily

Child Dose

Clinical InformationAdministration Information
Indication: Short-term management of haemorrhage
Age: Child
Dose: Oral – 25 mg/kg
Frequency: twice daily or three times daily
Indication: Management of hereditary angioedema
Age: Child
Dose: Oral – 25 mg/kg
Frequency: twice daily or three times daily

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment with serum creatinine concentration 120-250 micromol/l
Dose: Not specified – 15 mg/kg
Frequency: twice daily
Note: Adjust dose based on serum creatinine concentration
Condition: Renal impairment with serum creatinine concentration 250-500 micromol/l
Dose: Not specified – 15 mg/kg
Frequency: once daily
Note: Adjust dose based on serum creatinine concentration
Administration
  • Can be taken with or without food
  • Take 2-3 times daily as prescribed
Side Effect

Drug Interaction

Drug NameRisk Factors
Estrogens, Factor IX complex concentrates, anti-inhibitor coagulant concentrates
Potentially Fatal: Increased risk of thrombus formation
Tretinoin
Potentially Fatal: Increased risk of fatal thrombotic complications in acute promyelocytic leukaemia

Disease Interaction

Disease NameRisk Factors
Severe Renal Failure
Risk of accumulation
Active Intravascular Clotting
Risk of thrombosis

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a dry place at 15-30°C, away from light and keep out of children's reach.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.