Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Moderate to severe pain Age: Adult |
Dose: Oral – 50-100 mg Frequency: every 3-4 hours Note: maximum 600 mg daily |
|
Indication: Moderate to severe pain Age: Adult Condition: Hepatic impairment |
Dose: Oral – 50-100 mg Note: Reduce dose or avoid in liver disease |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Moderate to severe pain Age: 6-12 years |
Dose: Oral - 25 mg Frequency: every 3-4 hours |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment with Creatinine Clearance 10-50 ml/min |
Dose: Dosage Recommendation – 75% normal dose Note: Renal dose adjustment required |
|
Condition: Renal impairment with Creatinine Clearance less than 10 ml/min |
Dose: Dosage Recommendation – 50% normal dose Note: Renal dose adjustment required |
Administration
- Take with food
- Take after meals
Side Effect
- Physical dependence
- sedation
- dizziness
- euphoria
- lightheadedness
- alterations of mood
- respiratory depression
- visual hallucinations
- disorientation
- confusion
- hypertension
- tachycardia
- circulatory depression
- shock
- hypotension
- nausea
- vomiting
- constipation
- seizures
- diaphoresis
- rash
- blood dyscrasias
- local tissue damages (SC)
- muscle fibrosis (IM)
- Respiratory depression
- hypotension
- circulatory failure
- deepening coma
- convulsions
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Alcohol, CNS depressants
|
Depressant effects potentiated
|
|
Fluoxetine
|
May lead to diaphoresis, ataxia flushing and tremor associated with serotonin syndrome
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Head Injury
|
Risk of increased pressure
|
|
Narcotic Dependence
|
Risk of withdrawal or addiction
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.