Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute Bronchitis & Acute Exacerbations of Chronic Bronchitis, Otitis Media, Pharyngitis/Tonsillitis, Uncomplicated Urinary Tract Infections Age: Adult |
Dose: Oral – 200 or 400 mg Frequency: daily as a single dose or in two divided doses every 12 hours Note: In the treatment of infections due to Streptococcus pyogenes, a therapeutic dosage of cefixime should be administered for at least 10 days. |
|
Indication: Uncomplicated Gonorrhea (Alternative treatment of uncomplicated urogenital, anorectal, or pharyngeal gonorrhea if ceftriaxone unavailable) Age: Adult |
Dose: Oral – 400 mg Frequency: as a single dose Note: Plus azithromycin 1 g by mouth once. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Oral – 8 mg/kg/day Frequency: single dose (24 hourly) or divided into two doses (12 hourly) |
|
Age: Child Condition: convalescent oral therapy of serious infections |
Dose: Oral – up to 20 mg/kg/day Frequency: single dose (24 hourly) or divided into two doses (12 hourly) |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult Condition: Renal impairment |
Dose: Tablet – No dosage adjustment necessary Note: For use in patients with stable renal function |
|
Age: Adult Condition: Renal impairment |
Dose: Tablet – 260 mg Frequency: once daily Note: Administered by mouth; for use in patients with stable renal function |
Administration
- Can be taken with or without food
- Take at regular intervals
Side Effect
- Diarrhea (16%)
- Abdominal pain
- Candidiasis
- Dizziness
- Dyspepsia
- Elevated transaminases
- Eosinophilia
- Erythema multiforme
- Fever
- Flatulence
- Headache
- Increased blood urea nitrogen (BUN)
- Increased creatinine
- Leukopenia
- Nausea
- Prolonged prothrombin time (PT)
- Pruritus
- Pseudomembranous colitis
- Rash
- Serum sickness-like reaction
- Stevens-Johnson syndrome
- Thrombocytopenia
- Urticaria
- Vaginitis
- Vomiting
- Pseudomembranous colitis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Probenecid
|
Increased concentrations
|
|
Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban)
|
May increase prothrombin time
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for allergic reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30ºC temperature, protected from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.