Indication: Organophosphorous Poisoning

Age: Adults

Dose: Intravenous Infusion – 1-2 g

Duration: 15-30 minute infusion

Note: Repeat a second dose of 1 g to 2 g may be indicated after about one hour if muscle weakness has not been relieved. Additional doses may be given every 10-12 hours if muscle weakness persists. Use with atropine, which affects muscarinic receptors; pralidoxime's actions most striking at nicotinic sites (increase muscle strength 10-40 minutes).

Indication: Organophosphorous Poisoning

Age: Adults

Condition: Fluid restricted patient

Dose: Intravenous Injection – 1 g

Note: Should be slowly given (over not less than 5 minutes) by intravenous injection, as 50 mg/ml solution in normal saline (e.g. 1 g in 20 ml).

Indication: Organophosphorous Poisoning

Age: greater than 16 years

Dose: Intravenous Infusion – 1-2 g

Frequency: repeat a second dose of 1 g to 2 g after about one hour if muscle weakness has not been relieved

Note: 15-30 minute infusion. Additional doses every 10-12 hours if muscle weakness persists. Use with atropine.

Indication: Organophosphorous Poisoning

Age: greater than 16 years

Condition: fluid restricted patient

Dose: Intravenous Injection – 1 g

Note: should be slowly given (over not less than 5 minutes) by intravenous injection, as 50 mg/ml solution in normal saline (e.g. 1 g in 20 ml).

Condition: Renal Impairment

Dose: Not mentioned

Note: Reduce dose