Question 1

What is this medicine for, and how does it work?

Accepted Answer

Azilsartan + Chlorthalidone combination is used to control high blood pressure. Azilsartan dilates blood vessels, while Chlorthalidone removes excess water and salt from the body.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Can be taken with or without food • Take at same time each day • Take with water

Question 3

When should this medicine not be used?

Accepted Answer

• During pregnancy • In severe kidney disease • In high potassium

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Can cause low blood pressure • Use caution in kidney problems • May cause dizziness • Monitor kidney function • Avoid in pregnancy

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Contraindicated during pregnancy • May cause fetal harm • Discontinue as soon as pregnancy is detected

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Can cause low blood pressure • Use caution in kidney problems • May cause dizziness • Monitor kidney function • Avoid in pregnancy

Question 7

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For once-daily dosing: If you remember on the same day, take the dose. • For twice-daily dosing: If there's more than 8 hours until your next dose, take the missed dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 8

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Severe hypotension, electrolyte imbalance. • Treatment: Fluid therapy, electrolyte monitoring.

Question 9

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Dizziness, fatigue, low blood pressure, fainting • What to do: Monitor blood pressure, rise slowly from sitting/lying position, report severe dizziness; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 10

What is Azisan Plus 40/12.5 40mg+12.5mg used for?

Accepted Answer

Azisan Plus 40/12.5 40mg+12.5mg (Azilsartan + Chlorthalidone) is a pharmaceutical medicine manufactured by Renata Limited in Bangladesh. It is primarily prescribed for Hypertension (HTN), Initial Therapy in Patients Likely to Need Multiple Drugs to Help Achieve Blood Pressure Goals.

Question 11

What is the active generic component of Azisan Plus 40/12.5?

Accepted Answer

The active ingredient in Azisan Plus 40/12.5 is Azilsartan + Chlorthalidone, belonging to the Combined Antihypertensive Preparations drug class.

Question 12

What is the retail price of Azisan Plus 40/12.5 40mg+12.5mg in Bangladesh?

Accepted Answer

The official retail price of Azisan Plus 40/12.5 40mg+12.5mg (Tablet) is ৳22.00 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 13

What is the recommended dosage for Azisan Plus 40/12.5?

Accepted Answer

Standard adult dosage: Tablet – 1 tablet (40 mg/12.5 mg) (once daily). Pediatric dosage: Not specified. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 14

Is Azisan Plus 40/12.5 safe during pregnancy and breastfeeding?

Accepted Answer

Azisan Plus 40/12.5 is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 15

What are the common side effects of Azisan Plus 40/12.5?

Accepted Answer

**1-10%**; Dizziness (8.9%);Fatigue (2%);Hypotension (1.7%); **Less than 1%**; Syncope (0.3%);

Clinical Information	Administration Information
Indication: Hypertension Age: Adult	Dose: Tablet – 1 tablet (40 mg/12.5 mg) Frequency: once daily Note: May increase to 40 mg/25 mg after 2-4 weeks as needed to achieve blood pressure goals; not to exceed 40 mg/25 mg daily.
Indication: Hypertension Age: Adult Condition: Switching from ARB or diuretic monotherapy	Dose: Tablet – 40 mg/12.5 mg Frequency: once daily Note: Initiate by mouth.

Clinical Information	Administration Information
Condition: Renal impairment Mild-to-moderate (estimated Glomerular Filtration Rate 30 mL/min/1.73 square meter or greater)	Dose: Tablet – No dose adjustment required Note: Chlorthalidone may precipitate azotemia
Condition: Renal impairment Severe (estimated Glomerular Filtration Rate less than 30 mL/min/1.73 square meter)	Dose: Tablet – Safety and effectiveness not established Note: Chlorthalidone may precipitate azotemia

Drug Name	Risk Factors
NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac), including selective COX-2 inhibitors	May result in deterioration of renal function in elderly, volume-depleted patients or those with compromised renal function
Angiotensin receptor blockers, ACE Inhibitors (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril), aliskiren	Increased risks of hypotension, hyperkalemia & changes in renal function (including acute renal failure)

Disease Name	Risk Factors
Anuria	Can worsen kidney problems
Hypersensitivity	Can cause severe allergic reactions

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Renal Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources