Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Vitiligo Age: Adults and children 12 years of age and over |
Dose: Topical – Apply to the affected area of the skin Frequency: every 3 to 7 days Note: Apply 2 hours before ultraviolet exposure. The amount and time of UVA light for each treatment is based on skin type and response to treatment. Patient may have UVA light treatments 2 to 4 times a week when first starting and then less frequently as condition improves. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Vitiligo Age: Children 12 years of age and over |
Dose: Topical – Apply to the affected area of the skin Frequency: every 3-7 days Note: Apply 2 hours before ultraviolet exposure |
|
Indication: Vitiligo Age: less than 12 years old |
Dose: Topical – Safety and efficacy not established Note: Safety and efficacy not established |
Administration
- Apply before UVA exposure
- Protect surrounding skin
Side Effect
- Mild-moderate erythema x 24-48 hrs
- Nausea
- Pruritis
- Edema
- Dizziness
- Headache
- Malaise
- Depression
- Hypopigmentation
- Bullae formation
- Rash
- Herpes simplex
- Uritcaria
- GI disturbances
- Leg cramps
- Hypotension
- Extension of psoriasis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Drugs known to cause photosensitisation (e.g. anthralin, coal tar or derivatives, griseofulvin, phenothiazines, nalidixic acid, sulfonamides, tetracyclines, Thiazide diuretics (Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone))
|
Additive effects
|
|
Aminophylline, fluvoxamine, mexiletine, mirtazapine, ropinirole, theophylline, trifluoperazine, dexmedetomidine, ifosfamide
|
May increase the levels/effects
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Aphakia
|
Risk of severe eye damage
|
|
Existing or History of Melanoma
|
Risk of cancer progression
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 15-30° C. Protect from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.