Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Medical termination of pregnancy Age: Adult |
Dose: Tablet – 200 mg Frequency: Single oral dose Duration: Day 1 Note: Administration should be under the supervision of a qualified medical professional in a clinic, medical office, or hospital |
|
Indication: Medical termination of pregnancy Age: Adult |
Dose: Tablet – 800 micrograms (4 tablets of 200 micrograms) Frequency: Buccally (placed on each side of cheek and gum) Duration: 24-48 hours after ingesting Mifepristone tablet Note: Patient should wait for 30 minutes after placement; may need medication for cramps or gestational symptoms; patient should be given a phone number for questions |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Termination of pregnancy Age: 17 and younger |
Dose: Tablet – 200 mg Frequency: Single dose Note: Day 1; by mouth (oral) (mifepristone) |
|
Indication: Termination of pregnancy Age: 17 and younger |
Dose: Tablet – 800 mcg Frequency: Single dose Note: 24 to 48 hours later; buccal (misoprostol) |
Administration
- Take as directed by healthcare provider
- Follow exact timing
Side Effect
- nausea
- vomiting and diarrhea
- pelvic pain
- fainting
- headache
- dizziness and asthenia occurred rarely
- diarrhea
- abdominal pain
- nausea
- flatulence
- dyspepsia
- headache
- vomiting and constipation
- shivering
- hyperthermia
- dizziness
- pain due to uterine contractions
- severe vaginal bleeding
- shock
- pelvic pain
- uterine rupture (requiring surgical repair, hysterectomy and/or salpingo-oophorectomy)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Aspirin, NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac)
|
Decreased efficacy
|
|
Corticosteroids (Prednisone, Prednisolone, Methylprednisolone, Dexamethasone, Hydrocortisone)
|
Decreased efficacy, monitor patients during co-admin and for several days afterwards
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Ectopic Pregnancy
|
Risk of life-threatening complications
|
|
Chronic Adrenal Failure
|
Risk of hormonal imbalance
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protected from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.