Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is a combination medication that reduces pain and inflammation while protecting the stomach. One component reduces inflammation, while the other reduces stomach acid production.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Swallow whole with liquid • Take 30 minutes before meals • Do not crush or chew • Take at same time each day

Question 3

When should this medicine not be used?

Accepted Answer

• Take with food • Use caution if you have heart problems or high blood pressure • Avoid use in pregnant women starting at 30 weeks of gestation

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Take with food to reduce stomach upset • Do not lie down for 30 minutes after taking • Use caution if you have heart problems or high blood pressure • Long-term use may increase risk of stomach bleeding

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Not safe in late pregnancy • Avoid use in pregnant women starting at 30 weeks of gestation • May cause premature closure of fetal ductus arteriosus

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Take with food to reduce stomach upset • Do not lie down for 30 minutes after taking • Use caution if you have heart problems or high blood pressure • Long-term use may increase risk of stomach bleeding

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Lower doses may be required for elderly patients • Special monitoring needed for elderly

Question 8

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For inhalers: If more than 6 hours until your next dose, take the missed dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Vomiting, epigastric pain. • Lethargy, drowsiness. • Altered liver function.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Stomach pain, heartburn, nausea, dizziness, headache, digestive problems • What to do: Take with food, avoid alcohol, report black stools or severe stomach pain; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is Proxen Plus 20mg+375mg used for?

Accepted Answer

Proxen Plus 20mg+375mg (Esomeprazole + Naproxen) is a pharmaceutical medicine manufactured by Monicopharma Limited in Bangladesh. It is primarily prescribed for Ankylosing Spondylitis, Joint Stiffness, Osteoarthritis, Rheumatoid Arthritis (RA).

Question 12

What is the active generic component of Proxen Plus?

Accepted Answer

The active ingredient in Proxen Plus is Esomeprazole + Naproxen, belonging to the Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) drug class.

Question 13

What is the recommended dosage for Proxen Plus?

Accepted Answer

Standard adult dosage: Tablet – 375/20 or 500/20 mg (one tablet twice daily). Pediatric dosage: Oral Tablet – 375 mg naproxen/20 mg esomeprazole (twice daily). Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 14

Is Proxen Plus safe during pregnancy and breastfeeding?

Accepted Answer

Proxen Plus is classified under Pregnancy Category "C (first/second trimester), D (third trimester)". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 15

What are the common side effects of Proxen Plus?

Accepted Answer

In general;The most common adverse reactions in clinical trials (More than 5%) erosive gastritis; dyspepsia; gastritis; diarrhea; gastric ulcer; upper abdominal pain; nausea etc;

Clinical Information	Administration Information
Indication: Rheumatoid Arthritis	Dose: Tablet – 375/20 or 500/20 mg Frequency: one tablet twice daily
Indication: Osteoarthritis	Dose: Tablet – 375/20 or 500/20 mg Frequency: one tablet twice daily

Clinical Information	Administration Information
Indication: Juvenile idiopathic arthritis Age: 12 years of age and older	Dose: Oral Tablet – 375 mg naproxen/20 mg esomeprazole Frequency: twice daily Note: by mouth (oral)
Indication: Juvenile idiopathic arthritis Age: 12 years of age and older	Dose: Oral Tablet – 375 mg naproxen/20 mg esomeprazole or 500 mg naproxen/20 mg esomeprazole Frequency: twice daily Note: by mouth (oral)

Drug Name	Risk Factors
Digoxin	Increased risk of digoxin-induced cardiotoxic effects
Diuretics (Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone, Bumetanide, Ethacrynic acid, Furosemide, Torsemide, Amiloride, Eplerenone, Spironolactone, Triamterene)	Increased risk of hypomagnesaemia

Disease Name	Risk Factors
History of Asthma	Risk of bronchospasm
Urticaria	Risk of allergic reactions

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources