Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Gastro-oesophageal reflux disease
Age: Adult
Dose: Oral – 20 mg
Frequency: once daily in the morning
Duration: 4-8 weeks
Note: Elderly: No dosage adjustment needed. Hepatic impairment: No dosage adjustment needed.
Indication: Gastro-oesophageal reflux disease
Age: Adult
Condition: Maintenance
Dose: Oral – 10 or 20 mg
Frequency: once daily in the morning
Note: Elderly: No dosage adjustment needed. Hepatic impairment: No dosage adjustment needed.

Child Dose

Clinical InformationAdministration Information
Age: less than 1 year
Dose: Delayed-release capsule (sprinkles) – Safety and efficacy not established
Note: Safety and efficacy not established
Age: 1-11 years
Dose: Delayed-release capsule (sprinkles) – 5 mg
Frequency: once daily
Duration: for up to 12 weeks
Note: by mouth (oral) 30 minutes before a meal; may increase to 10 mg/day if inadequate response

Renal Dose

Clinical InformationAdministration Information
Age: Adult
Condition: Renal impairment
Dose: Tablet – Fixed dose
Note: Renal impairment: No dosage adjustment needed.
Administration
  • Can be taken with or without meals
  • Take at same time daily
Side Effect

Drug Interaction

Drug NameRisk Factors
Ketoconazole, Itraconazole, Clopidogrel
May decrease serum concentration
Diuretics (Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone, Bumetanide, Ethacrynic acid, Furosemide, Torsemide, Amiloride, Eplerenone, Spironolactone, Triamterene), Digoxin
Increased risk of hypomagnesaemia

Disease Interaction

Disease NameRisk Factors
Hypersensitivity
Can cause severe allergic reactions

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.