Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Osteoarthritis Age: Adult Condition: Upper extremities |
Dose: Topical/Cutaneous – 2 g Frequency: every 6 hours Note: Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals. Not to exceed 8 g per day to any single joint of upper extremities. |
|
Indication: Osteoarthritis Age: Adult Condition: Lower extremities |
Dose: Topical/Cutaneous – 4 g Frequency: every 6 hours Note: Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals. Not to exceed 16 g per day to any single joint of lower extremities. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Safety and efficacy not established Note: Not recommended |
Administration
- Apply to clean, dry skin
- Avoid showering for 30 minutes after application
Side Effect
- Dry skin (25-27%)
- Rash (20-35%)
- Contact dermatitis (19-33%)
- Pain (15-26%)
- Paresthesia (Less than 20%)
- Pruritus (52%)
- Exfoliation (6-24%)
- Hypertension
- Chest pain
- Skin ulcer
- Diarrhea
- Dyspepsia
- Alepesia
- Photosensitivity
- Edema
- Conjunctivitis
- Hematuria
- Asthma
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Methotrexate
|
May increase serum levels
|
|
Other NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac), Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban) (e.g. warfarin)
|
Higher risk of GI bleeding
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Active Peptic Ulcer
|
Risk of bleeding
|
|
Asthma
|
Can trigger asthma attack
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.