Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Mild to moderate hypertension Age: Adult |
Dose: Oral – 200 mg Frequency: once daily Note: Dose to be taken in the morning, then increased if necessary to 400 mg once daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Dosage – 100-200 mg Frequency: once daily |
|
Condition: Renal impairment |
Dose: Dosage – Avoid Note: Avoid use in patients with creatinine clearance less than 15 ml/min |
Administration
- Take on empty stomach
- Take at regular intervals
Side Effect
- Nausea
- abdominal discomfort
- diarrhoea
- CHF
- AV nodal block and bradycardia
- palpitations
- headache
- fatigue
- dizziness
- insomnia
- Raynaud's phenomenon
- orthostatic hypotension
- bronchial obstruction
- tremor
- rash
- muscle cramps
- impotence
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Clonidine
|
May exacerbate rebound hypertension upon withdrawal
|
|
Digitalis glycosides
|
May increase AV conduction time
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Sinus Bradycardia
|
Can dangerously slow heart rate
|
|
>1st Degree Heart Block
|
Can cause complete heart block
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep container in the outer carton. Do not store above 25°C. Do not use this medicine after the expiry date which is stated on the carton. The expiry date refers to the last day of that month. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.