Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Bone and joint infections, Respiratory tract infections, Genitourinary Tract Infections, Otitis Media Age: Adults |
Dose: Oral – 250 mg Frequency: every 6 hours Duration: 7 to 14 days Note: Adults 1 to 4 grams/day in divided doses. Duration of therapy ranges from 7 to 14 days depending on the infection type and severity. |
|
Indication: Bone and joint infections, Respiratory tract infections, Genitourinary Tract Infections, Otitis Media Age: Adults |
Dose: Oral – 500 mg Frequency: every 12 hours Duration: 7 to 14 days Note: Adults 1 to 4 grams/day in divided doses. Duration of therapy ranges from 7 to 14 days depending on the infection type and severity. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: greater than 15 years |
Dose: Dose – 250 mg Frequency: every 6 hours Note: Usual dose |
|
Age: greater than 15 years |
Dose: Dose – 500 mg Frequency: every 12 hours Note: May be administered |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment: Creatinine Clearance 40-50 ml/minute |
Dose: Not specified – Not specified Note: Maximum: 3 g daily |
|
Condition: Renal impairment: Creatinine Clearance 10-40 ml/minute |
Dose: Not specified – Not specified Note: Maximum: 1.5 g daily |
Administration
- Can be taken with or without food
- Take at evenly spaced times
Side Effect
- GI disturbances (eg nausea
- vomiting
- diarrhoea
- abdominal discomfort)
- dyspepsia
- allergic reactions (eg rash urticaria
- angioedema)
- genital and anal pruritus
- genital candidiasis
- vaginitis and vaginal discharge
- dizziness
- fatigue
- headache
- agitation
- confusion
- hallucinations
- arthralgia
- arthritis and joint disorders
- eosinophilia
- neutropenia
- thrombocytopenia
- haemolytic anaemia
- slightly elevated AST and ALT
- Rarely
- erythema multiforme
- Stevens-Johnson syndrome and toxic epidermal necrolysis
- cholestatic jaundice
- transient hepatitis
- Anaphylactic reactions
- nephrotoxicity
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Metformin
|
May result in fatal lactic acidosis
|
|
Warfarin
|
May enhance the anticoagulant effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for allergic reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Should be stored in cool and dry place.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.