Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Type 2 diabetes mellitus Age: Adult |
Dose: Oral – Initially, 10 mg Frequency: once daily Note: Administered in the morning; may be increased to 25 mg once daily if necessary for additional glycemic control. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Type 2 diabetes mellitus Age: 10 years and older |
Dose: Oral – 10 mg Frequency: Once daily Note: Maximum Dose: 25 mg once daily |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Creatinine Clearance less than 45 mL/minute |
Dose: Not specified Note: Contraindicated. |
|
Condition: Creatinine Clearance less than 60 mL/minute |
Dose: Not specified Note: Maximum: 10 mg daily. |
Administration
- Can be taken with or without food
- Take at same time each day
Side Effect
- Urinary Tract Infection (UTI) (7.6-9.3%)
- Female genital mycotic infections (5.4-6.4%)
- Upper respiratory tract infection (URTI) (3.1-4%)
- Increased urination (3.2-3.4%)
- Dyslipidemia (2.3-2.4%)
- Male genital mycotic infections (1.6-3.1%)
- Nausea (1.1-2.3%)
- Polydipsia (1.5-1.7%)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Insulin, insulin secretagogues (e.g. sulfonylureas)
|
Additive hypoglycaemic effect
|
|
Diuretics (e.g. thiazides, loop diuretics (Furosemide, Bumetanide, Ethacrynic acid, Torsemide))
|
Increased risk of dehydration and hypotension
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Type 1 Diabetes
|
Not approved for Type 1 DM
|
|
Severe Renal Impairment
|
Risk of further kidney damage
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a cool & dry place (below 30° C), protected from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.