Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Visceral Leishmaniasis Age: Adult |
Dose: Tablet – 100-150 mg/day Frequency: once daily Duration: 28 days Note: Administered by mouth (oral) |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Oral – 2.5 mg/kg/day Frequency: twice daily Note: by mouth (oral) |
|
Age: greater than 12 years |
Dose: Oral – 100 mg/day Frequency: twice daily Note: by mouth (oral) |
Administration
- Take with meals
- Complete full course
Side Effect
- Visceral leishmaniasis
- Increased transaminases
- Less than 3 x ULN (94%)
- Decreased platelets Less than 150,000 (62%)
- Vomiting (37.8%)
- Decreased appetite (23.1%)
- Diarrhea (20.4%)
- Visceral leishmaniasis
- Increased serum creatinineeatinine
- More than 1.5 x baseline (10%)
- Asthenia (6.3%)
- Increased transaminases
- 3-5 x ULN (6%)
- Decreased platelets Less than 50,000 (2.4%)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
No interactions listed
|
-
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Concurrent radiation therapy
|
Increased toxicity risk
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.