Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is an anti-cancer medication. It works by inhibiting a protein necessary for cancer cell growth, preventing their spread.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Can be taken with or without food • Swallow whole tablet • Do not break, crush or cut the tablet

Question 3

When should this medicine not be used?

Accepted Answer

• Do not use during pregnancy • Use with caution if bleeding risk • Use with caution in heart problems

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Monitor for heart rhythm changes • Use caution in patients with liver problems • May affect fetal development - avoid in pregnancy • Risk of bleeding - use caution with blood thinners

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• May cause fetal harm • Avoid use during pregnancy • Use effective contraception during and after treatment

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Monitor for heart rhythm changes • Use caution in patients with liver problems • May affect fetal development - avoid in pregnancy • Risk of bleeding - use caution with blood thinners

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Safety unknown under 18 years • Elderly may experience more side effects

Question 8

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For once-daily dosing: If you remember on the same day, take the dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Headache, vomiting, cytopenia. • Treatment: Blood count monitoring, supportive care.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Fluid retention, heart failure, diarrhea, headache, bleeding, fatigue, fever, skin rash, breathing problems • What to do: Regular blood tests required; Report breathing difficulties; Monitor weight changes; Avoid blood thinners; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is Mabic-20 20mg used for?

Accepted Answer

Mabic-20 20mg (Dasatinib) is a pharmaceutical medicine manufactured by Genvio Pharma Ltd. in Bangladesh. It is primarily prescribed for Acute Lymphoblastic Leukemia, Chronic Myeloid Leukemia.

Question 12

What is the active generic component of Mabic-20?

Accepted Answer

The active ingredient in Mabic-20 is Dasatinib, belonging to the Tyrosine Protein Kinase Inhibitors drug class.

Question 13

What is the retail price of Mabic-20 20mg in Bangladesh?

Accepted Answer

The official retail price of Mabic-20 20mg (Tablet) is ৳80.00 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 14

What is the recommended dosage for Mabic-20?

Accepted Answer

Standard adult dosage: Oral – 140 mg (once daily). Pediatric dosage: Tablet – Not recommended. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 15

Is Mabic-20 safe during pregnancy and breastfeeding?

Accepted Answer

Mabic-20 is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 16

What are the common side effects of Mabic-20?

Accepted Answer

**More than 10%**; Fluid retention, incl CHF; pulm edema; pleural effusion (50%);Diarrhea (49%);Headache (40%);Hemorrhage (40%);Fatigue (39%);Pyrexia (39%);Skin rash (35%);Infection (34%);Nausea (34%);Dyspnea (32%);Cough

Clinical Information	Administration Information
Indication: Philadelphia chromosome-positive (Ph+) Acute Lymphoblastic Leukemia (ALL) Age: Adults Condition: Resistance or intolerance to prior therapy	Dose: Oral – 140 mg Frequency: once daily Note: Initial dosage. May increase to 180 mg once daily if hematologic or cytogenetic response not achieved with initial dosage.
Indication: Chronic Myeloid Leukemia (CML) Condition: Newly diagnosed in chronic phase	Dose: Oral – 100 mg Frequency: once daily Note: May increase to 140 mg orally once daily if hematologic or cytogenetic response not achieved with initial dosage. Therapy was continued until disease progression or until no longer tolerated in clinical studies.

Clinical Information	Administration Information
Indication: Acute Lymphoblastic Leukemia Age: greater than 1 years	Dose: Tablet – Not recommended Note: Begin therapy on or before day 15 of induction chemotherapy; Continue therapy for 2 years
Indication: Acute Lymphoblastic Leukemia Age: greater than 1 years	Dose: Tablet – 40 mg Frequency: once daily Duration: 2 years Note: by mouth (oral); Begin therapy on or before day 15 of induction chemotherapy

Drug Name	Risk Factors
Alfentanil, cisapride, ciclosporin, fentanyl, pimozide, quinidine, simvastatin, sirolimus, tacrolimus, ergot alkaloids	May increase serum levels of these drugs
Antiplatelet drugs, Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban), NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac)	Increased risk of bleeding and thrombocytopenia

Disease Name	Risk Factors
Concurrent CYP3A4 Inhibitor Use	Risk of drug interactions
Pregnancy	Risk of fetal harm

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Renal Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources