Medicine Overview

Indication
Know Medicine, Follow Guideline

Adult Dose
Clinical InformationAdministration Information
Indication: Susceptible infections
Age: Adult
Condition: Mild infection
Dose: Deep Intramuscular or Slow Intravenous – 0.25-0.5 g
Frequency: every 8 hours
Note: Slow intravenous injection to be given over 3-5 minutes, or via intermittent or continuous intravenous infusion.
Indication: Susceptible infections
Age: Adult
Condition: Moderate to severe infection
Dose: Deep Intramuscular or Slow Intravenous – 0.5-1 g
Frequency: every 6-8 hours
Note: Slow intravenous injection to be given over 3-5 minutes, or via intermittent or continuous intravenous infusion.

Child Dose
Clinical InformationAdministration Information
Indication: Susceptible infections
Age: Child: greater than 1 year
Dose: Injection – 25-50 mg/kg daily
Frequency: in 3 or 4 divided doses
Note: to be given by deep intramuscular injection, slow intravenous injection over 3-5 minutes, or intermittent or continuous intravenous infusion. Maximum: 100 mg/kg daily in divided doses for severe infections.
Indication: Infections With Gram-Positive Cocci
Age: Neonates (less than 28 days)
Condition: less than 7 days
Dose: Intravenous/Intramuscular – 40 mg/kg/day
Frequency: divided every 12 hours

Renal Dose
Clinical InformationAdministration Information
Condition: Renal impairment with Creatinine Clearance less than 10 ml/min
Dose: Dosage – Half the usual dose
Frequency: every 18-24 hours
Condition: Renal impairment with Creatinine Clearance 11-34 ml/min
Dose: Dosage – Half the usual dose
Frequency: every 12 hours
Administration
  • Given as IV or IM injection
  • Must be administered by healthcare professionals
Side Effect

Drug Interaction
Drug NameRisk Factors
Vitamin K antagonists (e.g. warfarin)
May enhance anticoagulant effect
Sodium picosulfate, BCG and typhoid vaccine
May diminish therapeutic effect

Disease Interaction
Disease NameRisk Factors
No specific contraindications listed
Monitor for general drug reactions

Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
After reconstitution, Cefazolin is stable for 24 hours at room temperature or for 10 days if stored under refrigeration (5°C). Reconstituted solution may range in color from pale yellow to yellow without a change in potency.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.