Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Parkinson Disease Condition: Monotherapy |
Dose: Oral Tablet – 1 mg Frequency: once daily |
|
Indication: Parkinson Disease Condition: Adjunct without levodopa |
Dose: Oral Tablet – 1 mg Frequency: once daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: less than 18 years |
Dose: Not established Note: Safety and efficacy not established |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment: Mild-to-moderate |
Dose: Not specified Note: No dosage adjustment required |
|
Condition: Renal impairment: Severe |
Dose: Not specified Note: Not studied in severe renal impairment |
Administration
- Can be taken with or without food
- Take at same time each day
Side Effect
- EPS (dyskinesia/dystonia) (18%)
- Headache (14%)
- Nausea (10-12%)
- Postural hypotension (6-9%)
- Constipation (4-9%)
- Weight loss (2-9%)
- Arthralgia (7%)
- Dyspepsia (7%)
- Xerostomia (2-6%)
- Depression (5%)
- Fall (5%)
- Flu-like syndrome (5%)
- Hallucination (4-5%)
- Conjunctivitis (3%)
- Fever (3%)
- Gastroenteritis (3%)
- Rhinitis (3%)
- Arthritis (2%)
- Bruising (2%)
- Malaise (2%)
- Neck pain (2%)
- Parasthesia (2%)
- Vertigo (2%)
- CV
- MI
- Bundle branch block
- Gastrointestinal hemorrhage
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
CYP1A2 inhibitors (e.g. ciprofloxacin)
|
Increased plasma levels
|
|
Entacapone
|
Increased clearance
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe hepatic impairment
|
Can cause liver complications
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 30° c, protected from light and moisture. Keep all the medicines out of reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.