Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Susceptible infections Age: Adult |
Dose: Oral Suspension – 200 mg Frequency: Daily in divided doses |
|
Indication: Acne Age: Adult |
Dose: Oral Suspension – 50 mg Frequency: twice daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Susceptible infections Age: greater than 8 years |
Dose: Intravenous – 4 mg/kg Note: Initially, not to exceed the usual adult dose |
|
Indication: Susceptible infections Age: greater than 8 years |
Dose: Intravenous – 2 mg/kg Frequency: every 12 hours Note: Maintenance dose, not to exceed the usual adult dose |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Not specified – Not specified Note: Reduce dose or increase dosing interval. Maximum: 200 mg/day. |
Administration
- Can take with or without food
- Take with water
Side Effect
- Discoloration of teeth (in children)
- Vestibular symptoms (More than 30%)
- Pericarditis
- Myocarditis
- Vasculitis
- Angioedema
- Alopecia
- Erythema nodosum
- Erythematous rash
- Exfoliative dermatitis
- Pruritus
- Toxic epidermal necrolysis
- Urticaria
- Dizziness
- Fever
- Fatigue
- Somnolence
- Angioedema
- Hyperpigmentation of nails
- Pigmentation of skin and mucous membranes
- Thyroid dysfunction
- Thyroid discoloration
- Thyroid cancer
- Vulvovaginitis
- Hemolytic anemia
- Neutropenia
- Thrombocytopenia
- Agrunolocytosis
- Pancytopenia
- Hepatic cholestasis
- Hepatitis
- Hyperbilirubinemia
- Jaundice
- CNS effects
- Clostridium difficile diarrhea
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Calcium-containing antacids and other divalent or trivalent cations
|
Impaired absorption
|
|
Oral contraceptives
|
May decrease effectiveness
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protected from light, store below 25°C.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.