Medicine Overview

Indication
Know Medicine, Follow Guideline

Adult Dose
Clinical InformationAdministration Information
Age: Adult
Dose: Oral – 250–500 mg
Frequency: four times a day
Age: Adult
Dose: Oral – 0.5–1 g
Frequency: twice daily

Child Dose
Clinical InformationAdministration Information
Age: 7–11 years
Dose: Oral – 25–50 mg/kg
Frequency: in 2–4 divided doses daily
Note: by mouth (oral)
Age: 12–17 years
Dose: Oral – 250–500 mg
Frequency: 4 times a day
Note: by mouth (oral)

Renal Dose
Clinical InformationAdministration Information
Condition: Renal impairment for patients undergoing chronic intermittent haemodialysis
Dose: Dose – 250 mg
Frequency: repeat after 6-12 hours, then again 36-48 hours after the initial dose, and again at the start of the next haemodialysis if greater than 30 hours have elapsed since the previous dose
Note: given at the start of the session
Condition: Renal impairment with creatinine clearance greater than 20 ml/min
Dose: Dose – 500 mg
Frequency: every 6 hours
Administration
  • Can be taken with or without food
  • Take at regular intervals
Side Effect

Drug Interaction
Drug NameRisk Factors
loop diuretics (Furosemide, Bumetanide, Ethacrynic acid, Torsemide)
Increased risk of nephrotoxicity
Probenecid
Decreased renal clearance

Disease Interaction
Disease NameRisk Factors
Porphyria
Can trigger acute porphyria attacks

Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Cephradine Suspension should be freshly prepared. Reconstituted Suspension should be used within 7 days if kept at room temperature or within 14 days, if kept in a refrigerator. Cephradine Injection solutions should be used within 2 hours when kept at room temperature. When stored at 5°C, solutions retain potency for 12 hours. Reconstituted solutions may vary in colour from light to straw yellow; however, this does not affect the potency. Do not use later than the date of expiry. Keep all medicines out of the reach of children. To be dispensed only on the prescription of a registered physician

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.