Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Primary treatment of pulmonary and extrapulmonary tuberculosis Age: Adult |
Dose: Oral – 15 mg/kg/day Frequency: once daily Duration: Initial 8 weeks Note: Given with isoniazid, rifampicin and pyrazinamide. |
|
Indication: Primary treatment of pulmonary and extrapulmonary tuberculosis Age: Adult |
Dose: Oral – 30 mg/kg Frequency: thrice weekly Duration: Initial 8 weeks Note: Given with isoniazid, rifampicin and pyrazinamide. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Tuberculosis Age: Child |
Dose: Oral – 15–25 mg/kg Frequency: every 24 hours by mouth (oral) Note: maximum 2.5 g every 24 hours |
|
Indication: drug-resistant tuberculosis Age: Child |
Dose: Oral – 15-25 mg/kg Frequency: daily Note: by mouth (oral) |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Oral – Dose adjustment may be needed Note: Dose adjustment as determined by blood levels of ethambutol |
Administration
- Take with food
- Take with plenty of water
Side Effect
- Acute gout or hyperuricemia
- Abdominal pain
- Anaphylaxis
- Anorexia
- Confusion
- disorientation
- Fever
- Headache
- LFT abnormalities
- Malaise
- Nausea
- Optic neuritis
- symptoms may include decreased acuity
- color blindness or visual defects (usually revrsible with discontinuation, though irreversible blindness has been reported)
- Peripheral neuritis
- Pruritis
- Rash
- Vomiting
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Al hydroxide
|
Delayed or reduced absorption
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Optic Neuritis
|
Can cause vision loss
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 20-25°C. Protect from light, moisture and excessive heat.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.