Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Chronic idiopathic constipation Age: Adult |
Dose: Oral – 2 mg Frequency: once daily |
|
Indication: Chronic idiopathic constipation Age: Elderly |
Dose: Oral – 1 mg Frequency: once daily Note: Initially, may increase to 2 mg once daily if necessary. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Severe (Glomerular Filtration Rate less than 30 mL/min/1.73 m2) |
Dose: 1 mg Frequency: once daily |
|
Condition: Patient on dialysis |
Dose: Contraindicated Note: Contraindicated |
Administration
- Can be taken with or without food
- Take at regular intervals
Side Effect
- Nervous Headache
- dizziness
- fatigue
- malaise
- tremors
- CV Palpitations
- GI Nausea
- abdominal pain and distention
- diarrhoea
- vomiting
- flatulence
- dyspepsia
- anorexia
- rectal bleeding
- gastroenteritis
- Genitourinary Polyuria
- pollakiuria
- Musculoskeletal Muscle spasm
- Others Fever
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
P-glycoprotein/ABCB1 Inhibitors (Transport protein inhibitors)
|
Increased serum concentration
|
|
Atropine-like substance
|
Reduced effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Intestinal obstruction/perforation
|
Risk of bowel complications
|
|
Severe inflammatory bowel conditions
|
Can worsen inflammation
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at room temperature, below 30°C. Do not remove desiccant. Dispense in original bottle.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.