Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Drug-induced extrapyramidal symptoms
Age: Adult
Dose: Oral – 5-15 mg/day
Frequency: divided every 6-8 hours
Note: administered by mouth
Indication: Parkinson Disease
Age: Adult
Dose: Oral – Initially, 1 mg daily, gradually increased at intervals of 3-5 days by increments of 2 mg until 6-10 mg daily
Frequency: in 3-4 divided doses
Note: administered by mouth

Child Dose

Clinical InformationAdministration Information
Age: Child
Dose: Safety and efficacy – not established
Note: Safety and efficacy not established
Administration
  • Take with food
  • Take before meals if dry mouth occurs
Side Effect

Drug Interaction

Drug NameRisk Factors
Phenothiazines, clozapine, Antihistamines (Diphenhydramine, Loratadine, Levocetirizine, Cetirizine, Fexofenadine, Hydroxyzine, Bilastin), disopyramide, nefopam, amantadine
Increased antimuscarinic side effects
TCAs
Synergistic effect

Disease Interaction

Disease NameRisk Factors
Closed-Angle Glaucoma
Can increase eye pressure
Chronic Pulmonary Disease
Can worsen breathing

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Do not store above 30°C. Keep away from light and out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.