Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Depression with Anxiety Age: Adult |
Dose: Tablet – 1 tablet (5-10 mg chlordiazepoxide/12.5-25 mg amitriptyline) Frequency: three/four times daily by mouth Note: May increase to 6 tablets if necessary; 2 tablets reported to be effective in some patients. |
|
Age: Geriatric |
Dose: Tablet – 1 tablet (5 mg/12.5 mg) Frequency: three times daily by mouth Note: Avoid; strong anticholinergic and sedative effects; may cause orthostatic hypotension (Beers criteria). Consider alternatives; if must use, initiate with lower initial dose; long-acting active metabolites. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Form – Not specified Note: No approved pediatric dosage available |
Administration
- Take as directed
- Follow prescribed schedule
Side Effect
- Drowsiness
- Dry mouth
- Constipation
- Blurred vision
- Dizziness
- Bloating
- Vivid dreams
- Impotence
- Tremor
- Confusion
- Nasal congestion
- Edema
- Syncope
- Ataxia
- EEG abnormalities
- Menstrual irregularities
- Blood dyscrasias (agranulocytosis)
- Hepatic dysfunction (jaundice)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
No interactions listed
|
-
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Drug Hypersensitivity
|
Risk of allergic reaction
|
|
Severe Cardiovascular Disorders
|
Risk of heart complications
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protected from light. Keep all medicines out of reach of the children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.