Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Patients whose blood pressure is not adequately controlled with bisoprolol or amlodipine alone |
Dose: Tablet – 1 tablet Frequency: once daily Note: The recommended daily dose is 1 tablet of the given strength. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Mild to moderate renal impairment |
Dose: Tablet – Dosage adjustment not required Note: No dosage adjustment is required for patients with mild to moderate renal impairment |
|
Condition: Severe renal impairment (creatinine clearance less than 20 mL/min) |
Dose: Tablet – maximum 10 mg Frequency: once daily Note: In case of severe renal impairment (creatinine clearance less than 20 mL/min), the daily dose of the bisoprolol component of Bisoprolol + Amlodipine must not exceed 10 mg |
Administration
- Take at same time each day
- May be taken with or without food
Side Effect
- Edema
- headache
- increase heart rate
- sneezing
- fatigue
- leg cramps
- dry mouth
- Other adverse events reported were gastric irritation
- angina
- asthma
- cold extremities
- cough
- decrease in libido
- dizziness
- facial flushing
- postural hypotension
- skin rash
- sleep disturbance and vertigo
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
No interactions listed
|
-
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Cardiogenic Shock
|
Risk of cardiovascular collapse
|
|
Second/Third Degree AV Block
|
Risk of complete heart block
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 30° C, protects from light & moisture. Keep out of the reach of children
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.