Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Urinary Tract infection Age: Adult Condition: Acute uncomplicated |
Dose: Oral dosage & suspension – 250 mg Frequency: twice daily Duration: 3 days |
|
Indication: Urinary Tract infection Age: Adult Condition: Mild/Moderate |
Dose: Oral dosage & suspension – 250 mg Frequency: twice daily Duration: 7 to 14 days |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Oral – 20–40 mg/kg/day Frequency: twice daily Note: maximum 1.5 g/day |
|
Indication: Complicated Urinary Tract Infection and Pyelonephritis Age: Pediatric (1 to 17 years of age) |
Dose: Oral – 10–20 mg/kg Frequency: twice daily Duration: 10–21 days Note: maximum 750 mg per dose |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment with Creatinine Clearance greater than 50 mL/minute |
Dose: Not specified – Not specified Note: Dose adjustment not necessary |
|
Condition: Renal impairment with Creatinine Clearance 30-50 mL/minute |
Dose: Immediate-release – 250-500 mg Frequency: every 12 hours Note: by mouth |
Administration
- Can be taken with or without food
- Take with plenty of water
Side Effect
- Nausea (3%)
- Abdominal pain (2%)
- Diarrhea (2% adults
- 5% children)
- Increased aminotransferase levels (2%)
- Vomiting (1% adults
- 5% children)
- Headache (1%)
- Increased serum creatinineeatinine (1%)
- Rash (2%)
- Restlessness (1%)
- Acidosis
- Allergic reaction
- Angina pectoris
- Anorexia
- Arthralgia
- Ataxia
- Back pain
- Bad taste
- Blurred vision
- Breast pain
- Bronchospasm
- Diplopia
- Dizziness
- Drowsiness
- Dysphagia
- Dyspnea
- Flushing
- Foot pain
- Hallucinations
- Hiccups
- Hypertension
- Hypotension
- Insomnia
- Irritability
- Joint stiffness
- Lethargy
- Migraine
- Nephritis
- Nightmares
- Oral candidiasis
- Palpitation
- Photosensitivity
- Polyuria
- Syncope
- Tachycardia
- Tinnitus
- Tremor
- Urinary retention
- Vaginitis
- Anaphylactoid reaction
- cardiopulmonary arrest
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Clozapine, Ropinirole, Theophylline
|
May increase plasma concentrations
|
|
Warfarin, Glibenclamide
|
Enhances effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Exposure To Strong Sunlight Or Sun Lamps
|
Risk of severe photosensitivity
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, protected from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.