Medicine Overview

Indication
Know Medicine, Follow Guideline

Adult Dose
Clinical InformationAdministration Information
Indication: Hypertension
Dose: Oral – 5 mg/20 mg
Frequency: once daily
Note: Initially; may increase the dose after 1-2 weeks; not to exceed 10 mg/40 mg. May be administered concomitantly with other antihypertensive agents.

Child Dose
Clinical InformationAdministration Information
Age: Pediatric
Dose: Tablet – No approved pediatric dosage available
Note: Not recommended

Renal Dose
Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Not mentioned
Note: Avoid use in severe renal impairment (Creatinine Clearance less than 20 mL/minute)
Administration
  • Take with or without food
  • Take once daily
Side Effect

Drug Interaction
Drug NameRisk Factors
ACE Inhibitors (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril), Potassium-sparing diuretics (Amiloride, Eplerenone, Spironolactone, Triamterene), K salts, K supplements
Increased risk of hyperkalaemia
Other Antihypertensive (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, Propranolol, Metoprolol, Atenolol, Carvedilol, Bisoprolol, Nadolol, Amlodipine, Diltiazem, Verapamil, Nifedipine, Nicardipine, Hydrochlorothiazide, Chlorthalidone, Indapamide, Furosemide, Bumetanide, Torsemide, Spironolactone, Amiloride, Triamterene, Prazosin, Doxazosin, Terazosin, Clonidine, Methyldopa, Hydralazine, Minoxidil)
May potentiate BP lowering effects

Disease Interaction
Disease NameRisk Factors
Biliary Obstruction
Risk of complications

Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Do not store above 30°C. Keep away from light and out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.