Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is also an opioid pain reliever. It's used for pain control during surgery. It works by acting on opioid receptors in the brain and nervous system to reduce the sensation of pain.

Question 2

When and how should this medicine be taken?

Accepted Answer

• For IV use only • Must be diluted before administration • Given as injection over 30-60 seconds or as continuous infusion • Should only be administered by trained healthcare professionals

Question 3

When should this medicine not be used?

Accepted Answer

• In severe respiratory problems • In severe cardiac problems • In head injury • When taking alcohol or tranquilizers • In myasthenia gravis

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• For hospital use only • Can cause severe breathing problems • May be habit-forming • Tell doctor if you have heart problems • Careful monitoring required during use

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• May cause neonatal opioid withdrawal syndrome with prolonged use • Insufficient data to determine risk of birth defects or miscarriage • May cause respiratory depression in newborns • Not recommended during labor and delivery

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• For hospital use only • Can cause severe breathing problems • May be habit-forming • Tell doctor if you have heart problems • Careful monitoring required during use

Question 7

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For twice-daily dosing: If more than 6 hours until your next dose, take the missed dose. • For once-daily dosing: If you remember on the same day, take the dose. • Take your next dose at the regular time. • If you miss multiple doses, contact your doctor.

Question 8

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Severe respiratory depression, unconsciousness, miosis. • Treatment: Naloxone, airway management, mechanical ventilation.

Question 9

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Nausea, vomiting, respiratory depression, slow heart rate, muscle rigidity • What to do: Medical supervision required; Monitor breathing; Report chest tightness; Follow recovery instructions; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 10

What is Remifen 1mg/vial used for?

Accepted Answer

Remifen 1mg/vial (Remifentanil) is a pharmaceutical medicine manufactured by Incepta Pharmaceuticals Ltd. in Bangladesh. It is primarily prescribed for Analgesia & Sedation in Ventilated Patients Under Intensive Care, Analgesia during Induction of Anesthesia, Analgesia during Maintenance of Anaesthesia in Ventilated Patients, Analgesia in Cardiac Anaesthesia, Continuation of Analgesia Into Immediate Postoperative Period.

Question 11

What is the active generic component of Remifen?

Accepted Answer

The active ingredient in Remifen is Remifentanil, belonging to the Opioid Analgesics drug class.

Question 12

What is the retail price of Remifen 1mg/vial in Bangladesh?

Accepted Answer

The official retail price of Remifen 1mg/vial (IV Injection) is ৳200.00 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 13

What is the recommended dosage for Remifen?

Accepted Answer

Standard adult dosage: Intravenous – Infuse at 0.5-1 mcg/kg/minute. Pediatric dosage: Intravenous infusion – 0.4-1.0 mcg/kg/minute. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 14

Is Remifen safe during pregnancy and breastfeeding?

Accepted Answer

Remifen is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 15

What are the common side effects of Remifen?

Accepted Answer

**More than 10%**; Nausea;Vomiting; **1-10%**; Respiratory depression;Bradycardia (dose dependent);Hypertension;Hypotension (dose dependent);Tachycardia;Skeletal muscle rigidity (dose dependent);Postoperative pain;Shiver

Clinical Information	Administration Information
Indication: Analgesia during induction of anesthesia Age: Adult	Dose: Intravenous – Infuse at 0.5-1 mcg/kg/minute Note: To be used in conjunction with an hypnotic agent (e.g. propofol, thiopentone, isoflurane). If the patient is to be intubated less than 8 minutes after the start of the infusion, an additional initial intravenous bolus of 1 mcg/kg may be given over 30-60 seconds.
Indication: Analgesia during maintenance of anesthesia Age: Adult Condition: Ventilated patients	Dose: Intravenous – 0.05-2 mcg/kg/minute Note: Usual infusion doses range depending on the anesthetic drug used and titrated according to patient response. In response to light anesthesia or intense surgical stress, supplemental intravenous boluses of 0.5-1 mcg/kg may be administered every 2-5 minutes.

Clinical Information	Administration Information
Indication: Intravenous Analgesia during maintenance of anaesthesia in ventilated patients Age: Neonates	Dose: Intravenous infusion – 0.4-1.0 mcg/kg/minute Note: depending on the anaesthetic method and adjust according to patient response, supplemental intravenous injection of 1 mcg/kg dose may be given
Indication: Intravenous Analgesia during maintenance of anaesthesia in ventilated patients Age: 1-12 yr	Dose: Intravenous injection – initially 0.1-1 mcg/kg Note: over at least 30 seconds (excluded if not needed)

Drug Name	Risk Factors
Inhaled and IV anesthetics, Benzodiazepines (Diazepam, Alprazolam, Lorazepam, Clonazepam, Midazolam)	Increased CNS depression
Cardiac depressants (e.g. β-blockers, Calcium Channel Blockers (Amlodipine, Diltiazem, Verapamil, Nifedipine, Felodipine, Nicardipine, Isradipine))	Increased hypotension and bradycardia

Disease Name	Risk Factors
Epidural/Intrathecal Administration	Risk of glycine toxicity
Sole Anesthesia Agent	Insufficient for complete anesthesia

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources