Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is an immunosuppressant medication that prevents organ rejection after transplantation and treats certain cancers. It works by inhibiting mTOR protein, suppressing T-cell activation.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Take consistently with or without food • Take at same time daily • Avoid grapefruit

Question 3

When should this medicine not be used?

Accepted Answer

• Take at the same time each day • May increase risk of infections • Do not take live vaccines • Can cause fetal harm

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Take at the same time each day • May increase risk of infections - wash hands frequently • Do not take live vaccines during treatment • Tell your doctor if you have trouble breathing or swelling

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Can cause fetal harm • Advise pregnant women of potential risk to fetus • Use effective contraception during treatment and for 8 weeks after last dose

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Take at the same time each day • May increase risk of infections - wash hands frequently • Do not take live vaccines during treatment • Tell your doctor if you have trouble breathing or swelling

Question 7

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For once-daily dosing: If you remember on the same day, take the dose. • If you remember the next day, skip the missed dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 8

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Headache, vomiting. • Mouth ulcers. • Treatment: Blood monitoring, supportive care.

Question 9

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Mouth sores, constipation, infections, weakness, fatigue, cough, diarrhea, rash • What to do: Regular blood tests, maintain good oral hygiene, report fever or breathing problems; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 10

What is Afinitor 5mg used for?

Accepted Answer

Afinitor 5mg (Everolimus) is a pharmaceutical medicine manufactured by Novartis (Bangladesh) Ltd. in Bangladesh. It is primarily prescribed for Astrocytoma, Breast Cancer, Kidney Cancer, Liver Transplant, Neuroendocrine Tumors, Renal Angiomyolipoma, Renal Cell Carcinoma, Renal Transplantation, Tuberous Sclerosis Complex.

Question 11

What is the active generic component of Afinitor?

Accepted Answer

The active ingredient in Afinitor is Everolimus, belonging to the Immunosuppressant drug class.

Question 12

What is the retail price of Afinitor 5mg in Bangladesh?

Accepted Answer

The official retail price of Afinitor 5mg (Tablet) is ৳5.00 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 13

What is the recommended dosage for Afinitor?

Accepted Answer

Standard adult dosage: Oral - 10 mg (once daily). Pediatric dosage: By mouth – 4.5 mg/m2 (once daily). Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 14

Is Afinitor safe during pregnancy and breastfeeding?

Accepted Answer

Afinitor is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 15

What are the common side effects of Afinitor?

Accepted Answer

**More than 10%**; Stomatitis (44%);Constipation (38%);Infections (37%);Asthenia (33%);Fatigue (31%);Cough (30%);Diarrhea (30%);Rash (29%);Anemia (26%);Nausea (26%);Anorexia (25%);Edema; peripheral (25-45%);Dyspnea (24%)

Clinical Information	Administration Information
Indication: Breast Cancer Age: Adult	Dose: Oral - 10 mg Frequency: once daily Note: with or without food
Indication: Renal Cell Carcinoma Age: Adult	Dose: Oral - 10 mg Frequency: once daily Note: with or without food

Clinical Information	Administration Information
Indication: Tuberous Sclerosis Complex (TSC)-associated subependymal giant cell astrocytoma (SEGA) Age: 1 year and older	Dose: By mouth – 4.5 mg/m2 Frequency: once daily Note: by mouth (oral)
Indication: Tuberous Sclerosis Complex (TSC)-associated partial-onset seizures Age: 2 years and older	Dose: By mouth – 5 mg/m2 Frequency: once daily Note: by mouth (oral)

Drug Name	Risk Factors
CYP3A4 inhibitors & inducers, CYP2D6 substrates with narrow therapeutic index, PgP inhibitors, Rifampicin, ACE Inhibitors (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril)	Interaction
Grapefruit juice & live vaccines	Interaction

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources