Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is a blood-thinning medication. It's used to prevent blood clots. It works by inhibiting a blood protein called thrombin.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Take with or without food • Swallow capsule whole • Do not break, crush or chew • Take at the same time each day

Question 3

When should this medicine not be used?

Accepted Answer

• Serious bleeding • Artificial heart valves • Blood clots • Kidney problems

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• May cause serious and fatal bleeding • Not recommended for patients with artificial heart valves • May increase risk of blood clots if stopped abruptly • Use caution in patients with kidney problems

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Risk of bleeding in mother and fetus • Monitor neonates for bleeding • Consider discontinuation or use of shorter acting anticoagulant as delivery approaches

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• May cause serious and fatal bleeding • Not recommended for patients with artificial heart valves • May increase risk of blood clots if stopped abruptly • Use caution in patients with kidney problems

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Safety unknown in children • 82% of study patients were over 65

Question 8

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For once-daily dosing: If you remember on the same day, take the dose. • For twice-daily dosing: If more than 6 hours until your next dose, take the missed dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Excessive bleeding, hemorrhage. • Treatment: Charcoal, idarucizumab, coagulation parameter monitoring.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Digestive problems, nausea, vomiting, bleeding risk • What to do: Take with food; Report unusual bleeding; Regular monitoring; Don't skip doses; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is Dabiran 110mg used for?

Accepted Answer

Dabiran 110mg (Dabigatran etexilate) is a pharmaceutical medicine manufactured by Healthcare Pharmaceuticals Ltd. in Bangladesh. It is primarily prescribed for Atrial Fibrillation, Deep Vein Thrombosis (DVT), Prevention of Stroke, Prophylaxis of Postoperative Venous Thromboembolism, Pulmonary Embolism.

Question 12

What is the active generic component of Dabiran?

Accepted Answer

The active ingredient in Dabiran is Dabigatran etexilate, belonging to the Oral Anti-Coagulants drug class.

Question 13

What is the retail price of Dabiran 110mg in Bangladesh?

Accepted Answer

The official retail price of Dabiran 110mg (Capsule) is ৳95.00 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 14

What is the recommended dosage for Dabiran?

Accepted Answer

Standard adult dosage: Oral – Initially, 110 mg, followed by 220 mg (once daily). Pediatric dosage: Capsule – 75 mg (twice daily). Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 15

Is Dabiran safe during pregnancy and breastfeeding?

Accepted Answer

Dabiran is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 16

What are the common side effects of Dabiran?

Accepted Answer

**More than 10%**; Dyspepsia and gastritis (35%, compared with warfarin [24%]);Any bleed (16.6%, compared with warfarin [18.4%]); **1-10%**; Major bleed (3.3%; compared with warfarin [3.6%]);Life-threatening bleed (1.5%,

Clinical Information	Administration Information
Indication: Prophylaxis of postoperative venous thromboembolism/Prophylaxis of DVT and PE following total Knee replacement surgery Age: Adult 18–74 years	Dose: Oral – Initially, 110 mg, followed by 220 mg Frequency: once daily Duration: 10 days Note: Initial dose to be taken 1–4 hours after surgery, followed by 220 mg once daily starting on the first day after surgery. Reduce dose to 150 mg once daily if given concurrently with amiodarone, verapamil or quinidine.
Indication: Prophylaxis of postoperative venous thromboembolism/Prophylaxis of DVT and PE following total Hip replacement surgery Age: Adult 18–74 years	Dose: Oral – Initially, 110 mg, followed by 220 mg Frequency: once daily Duration: 28–35 days Note: Initial dose to be taken 1–4 hours after surgery, followed by 220 mg once daily starting on the first day after surgery. Reduce dose to 150 mg once daily if given concurrently with amiodarone, verapamil or quinidine.

Clinical Information	Administration Information
Indication: Treatment of venous thromboembolic events (VTE) Age: 8 to less than 18 years Condition: after at least 5 days of parenteral anticoagulant	Dose: Capsule – 75 mg Frequency: twice daily Note: by mouth (oral), swallow the capsule whole
Indication: Treatment of venous thromboembolic events (VTE) Age: 8 to less than 18 years Condition: after at least 5 days of parenteral anticoagulant	Dose: Capsule – 110 mg Frequency: twice daily Note: by mouth (oral), swallow the capsule whole

Clinical Information	Administration Information
Indication: Prophylaxis of postoperative venous thromboembolism Condition: Renal impairment with Creatinine Clearance less than 30 ml/minute	Dose: Tablet – Dosage not specified Note: Contraindicated
Indication: Prophylaxis of postoperative venous thromboembolism Condition: Renal impairment with Creatinine Clearance 30-50 ml/minute (Knee replacement)	Dose: Tablet – Initial: 75 mg followed by 150 mg Frequency: Initial dose within 1-4 hours after surgery followed by once daily Duration: Total of 10 days Note: Maximum 75 mg in patients taking with verapamil

Drug Name	Risk Factors
NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac)	May increase risk of bleeding
Clarithromycin	May increase serum levels of dabigatran

Disease Name	Risk Factors
Active bleeding	Risk of severe hemorrhage
Prosthetic heart valve	Risk of valve thrombosis

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Renal Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources