Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Moderate-to-severe dyspareunia due to menopause |
Dose: Oral dose – 60 mg Frequency: once daily Note: Use for the shortest duration consistent with treatment goals and risks for the individual woman. |
|
Indication: Moderate-to-severe vaginal dryness due to menopause |
Dose: Oral dose – 60 mg Frequency: once daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: HIV Infection Age: Pediatric |
Dose: Oral Tablet – 1 tablet Note: Not recommended |
|
Indication: HIV Infection Age: Pediatric |
Dose: Oral Tablet – 1 tablet Frequency: twice daily Note: by mouth (oral) |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Not specified Note: No dosage adjustment required |
Administration
- Take with food
- Food increases absorption
Side Effect
- Hot flush (7.5%)
- Vaginal discharge (3.8%)
- Muscle spasms (3.2%)
- Hyperhidrosis (1.6%)
- Genital discharge (1.3%)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Estrogen, estrogen agonist/antagonist
|
Should not be used concomitantly
|
|
Fluconazole, ketoconazole
|
Do not use concomitantly as they increase serum concentrations of Ospemifene
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Undiagnosed Abnormal Genital Bleeding
|
May mask serious conditions
|
|
Known/Suspected Estrogen-Dependent Neoplasia
|
May stimulate tumor growth
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.