Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Induction of general anaesthesia Age: Adult Condition: Premedicated patient |
Dose: Inhalation – Up to 5% volume/volume with oxygen (or mixture of oxygen and nitrous oxide) Note: Individualised according to age and clinical status. Doses are given via calibrated vaporiser. |
|
Indication: Induction of general anaesthesia Age: Adult Condition: Unpremedicated patient |
Dose: Inhalation – Up to 8% volume/volume Note: Doses are given via calibrated vaporiser. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Induction of general anesthesia Age: Child |
Dose: Inhalation – Up to 7% volume/volume with oxygen (or mixture of oxygen and nitrous oxide) Note: given via calibrated vaporizer |
|
Indication: Maintenance of general anesthesia Age: Child |
Dose: Inhalation – Up to 7% volume/volume with oxygen (or mixture of oxygen and nitrous oxide) Note: given via calibrated vaporizer |
Administration
- For hospital use only
- Must be administered by anesthesiologist
Side Effect
- Cardiorespiratory depression
- hypotension
- bradycardia
- laryngospasm
- increased cough and salivation
- urinary retention
- acute renal failure
- changes in liver enzyme values
- liver damage
- nausea
- vomiting
- delirium
- seizure
- rash
- urticaria
- pruritus
- dyspnoea
- wheezing
- chest discomfort
- bronchospasm
- anaphylactic/anaphylactoid reaction
- agitation
- dystonic movements (childn)
- Malignant hyperthermia
- Rarely
- hyperkalaemia resulting in cardiac arrhythmias
- particularly in childn w/ neuromuscular disease
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Competitive neuromuscular blockers
|
May enhance effect and duration
|
|
Isoniazid, Alcohol
|
Metabolism and toxicity increased
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Malignant Hyperthermia
|
Risk of severe reaction
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 15-30° C. Protect from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.