Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is a combination local anesthetic used in spinal anesthesia. One component causes numbness, while the other enhances the anesthetic effect.

Question 2

When and how should this medicine be taken?

Accepted Answer

• For medical professional use only • Must be administered in clinical setting • Patient must be monitored during administration • Follow proper sterile technique

Question 3

When should this medicine not be used?

Accepted Answer

• Caution in elderly/weak • Caution in heart problems • Caution in breathing difficulties

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Use carefully in elderly or weak patients • Be cautious in patients with heart problems • Use with care in patients with breathing difficulties

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• No specific precautions mentioned • Consult doctor before use

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Use carefully in elderly or weak patients • Be cautious in patients with heart problems • Use with care in patients with breathing difficulties

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Not safe under 12 years in spinal anesthesia. • Elderly require special attention. • Use caution in kidney problems.

Question 8

What should be done if a dose is missed?

Accepted Answer

• For injection: Consult doctor. • Don't self-administer missed dose. • Inform doctor at next appointment.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Symptoms: CNS toxicity, cardiac arrhythmias. • Treatment: Airway protection, oxygen, lipid emulsion therapy. • Complications: Convulsions, cardiac arrest.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Low blood pressure, slow heartbeat, irregular heartbeat, seizures, restlessness, dizziness, numbness, breathing problems, cardiac arrest • What to do: Use only under medical supervision; Monitor vital signs closely; Report any chest pain or breathing difficulty immediately; Keep emergency equipment ready; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is Duracain 20mg+320mg used for?

Accepted Answer

Duracain 20mg+320mg (Bupivacaine + Dextrose) is a pharmaceutical medicine manufactured by Techno Drugs Ltd. in Bangladesh. It is primarily prescribed for Epidural Anesthesia, Intrathecal Anesthesia, Spinal Anesthesia, Subarachnoid Anesthesia.

Question 12

What is the active generic component of Duracain?

Accepted Answer

The active ingredient in Duracain is Bupivacaine + Dextrose, belonging to the Regional Anesthesia drug class.

Question 13

What is the retail price of Duracain 20mg+320mg in Bangladesh?

Accepted Answer

The official retail price of Duracain 20mg+320mg (Capsule) is ৳4.17 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 14

What is the recommended dosage for Duracain?

Accepted Answer

Standard adult dosage: Injection – 9 mg with adrenaline (1 in 200,000) (May repeat 2-10 minutes later if needed). Pediatric dosage: Not recommended. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 15

Is Duracain safe during pregnancy and breastfeeding?

Accepted Answer

Duracain is classified under Pregnancy Category "C". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 16

What are the common side effects of Duracain?

Accepted Answer

**CNS excitation may be followed by**; depression; Hypotension; bradycardia; arrhythmias and cardiac arrest; methaemoglobinaemia; seizures; restlessness; dizziness; Hypersensitivity; Prolonged block; Edema; Headache; Hyp

Clinical Information	Administration Information
Indication: Percutaneous infiltration anesthesia Age: Adult Condition: For prolonged action	Dose: Injection – 9 mg with adrenaline (1 in 200,000) Frequency: May repeat 2-10 minutes later if needed Note: Maximum: 90 mg per dental sitting
Indication: Surgical anesthesia (Peripheral nerve block) Age: Adult	Dose: Injection – 12.5 mg (as 0.25% solution) Note: Maximum: 150 mg per dose

Clinical Information	Administration Information
Age: less than 12 years Condition: Caudal Block, Epidural Block, Local Block	Dose: Not recommended Note: Not recommended
Indication: Local Anesthesia: Infiltration Age: greater than 12 years	Dose: Infiltration 0.25% – 175 mg Note: infiltrated locally; 175 mg maximum

Drug Name	Risk Factors
Other local anaesthetics, amide-type local anaesthetics	Additive systemic toxic effect
Antiarrhythmics (Amiodarone, Flecainide, Propafenone, Quinidine, Disopyramide, Procainamide)	Increased risk of myocardial depression

Disease Name	Risk Factors
IV Regional Anaesthesia	Risk of systemic toxicity
Paracervical Block in Obstetrics	Risk to fetus

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources