Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Allergic and inflammatory disorders Age: Adult |
Dose: Oral – 3–18 mg Frequency: daily Note: Usual maintenance dose; for acute disorders, initially up to 120 mg daily. |
|
Indication: Rheumatoid arthritis Age: Adult |
Dose: Oral – 3-18 mg Frequency: daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Allergic and inflammatory disorders Age: 1 month–11 years |
Dose: Oral – 0.25–1.5 mg/kg Frequency: daily or on alternate days Note: by mouth (oral) |
|
Indication: Allergic and inflammatory disorders Age: 1 month–11 years Condition: emergency situations |
Dose: Oral – up to 2.4 mg/kg Frequency: daily Note: maximum 120 mg; by mouth (oral) |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment: Mild, moderate, or severe |
Dose: No dose adjustment required Note: No dose adjustment required for mild, moderate, or severe renal impairment |
Administration
- Can take with or without food
- Take at regular times
Side Effect
- GI disturbances
- musculoskeletal
- endocrine
- neuropsychiatric
- ophthalmic
- fluid and electrolyte disturbances
- susceptible to infection
- impaired healing
- hypersensitivity
- skin atrophy
- striae
- telangiectasia
- acne
- myocardial rupture following recent MI
- thromboembolism
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Antacids, ACE Inhibitors (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril), acetazolamide, Adrenergic Neuron Blockers (Guanethidine, Bretylium, Reserpine), Antidiabetics (Metformin, Glibenclamide, Glimepiride, Sitagliptin, Pioglitazone, Rosiglitazone, Empagliflozin), aspirin, barbiturate, β-blockers, calcium-channel blockers, carbamazepine, carbenoxolone, cardiac glycosides, clonidine, coumarins, diazoxide, diuretics, erythromycin, hydralazine, ketoconazole, methotrexate, methyldopa, mifepristone, minoxidil, moxonidine, nitrates, nitroprusside, NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac), oestrogens, phenytoin, primidone, rifamycins, ritonavir, somatropin, β2 Sympathomimetics (Ephedrine, Pseudoephedrine, Phenylephrine), theophylline, vaccines
|
Interactions mentioned but specific effects not detailed
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Systemic Infection
|
Risk of infection worsening
|
|
Live Virus Vaccines
|
Risk with immunosuppressive doses
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool (below 25°C) and dry place, protected from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.