Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Rheumatoid arthritis Age: Adult |
Dose: Subcutaneous – 25 mg Frequency: twice weekly at intervals of 3-4 days Note: Discontinue treatment if no response after 6 months. |
|
Indication: Rheumatoid arthritis Age: Adult |
Dose: Subcutaneous – 50 mg Frequency: once weekly Note: Discontinue treatment if no response after 6 months. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Juvenile idiopathic arthritis Age: greater than 2 years |
Dose: Subcutaneous – 0.4 mg/kg Frequency: twice weekly at intervals of 3-4 days Note: maximum: 25 mg; Discontinue treatment if no response after 6 months or initial response is not maintained |
|
Indication: Juvenile idiopathic arthritis Age: greater than 2 years |
Dose: Subcutaneous – 0.8 mg/kg Frequency: once weekly Note: maximum: 50 mg; Discontinue treatment if no response after 6 months or initial response is not maintained |
Administration
- Inject subcutaneously
- Rotate injection sites
Side Effect
- RA
- Infection (81%)
- Upper respiratory infections (65%)
- Non-upper respiratory infections (54%)
- Injection site reactions (43%)
- Diarrhea (16%)
- Rash (13%)
- RA
- Pruritus (5%)
- Pyrexia (2%)
- Urticaria (2%)
- Hypersensitivity (1%)
- Serious infections and sepsis (eg TB, invasive fungal infections)
- malignancies (eg breast, lung and skin cancers, lymphoma)
- Rarely
- pancytopenia
- aplastic anaemia
- central and peripheral demyelinating events
- lupus
- lupus-related conditions and vasculitis
- anaphylaxis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
No specific drug interactions mentioned
|
May interfere with troponin determinations; other assays using murine monoclonal antibodies
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Sepsis or Risk of Sepsis
|
Increased risk of serious infections
|
|
Active Infections including Chronic or Localised Infections
|
May worsen existing infections
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Etanercept should be stored in refrigerator at 2-8°C. Do not freeze. Do not shake. Keep away from light. Keep out of reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.