Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Prevention of ischaemic events Age: Adult Condition: Oral |
Dose: Tablet – clopidogrel 75 mg and aspirin 75 mg Frequency: 1 tablet once daily |
|
Indication: Acute coronary syndrome Age: Adult Condition: Oral loading dose |
Dose: Tablet – clopidogrel 75 mg and aspirin 75 mg Frequency: 4 tablets once |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Form – Not specified Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment: Creatinine Clearance (ml/min) less than 10 |
Dose: Dose: Note: Avoid use |
Administration
- Take with food
- Take at same time daily
Side Effect
- Aspirin GI disturbances
- epigastric discomfort
- prolonged bleeding time
- rhinitis
- urticaria
- angioedema
- salicylism
- tinnitus
- Clopidogrel Dyspepsia
- abdominal pain
- nausea
- vomiting
- flatulence
- constipation
- gastritis
- gastric and duodenal ulcers
- Serious events include bleeding and GI haemorrhage
- GI upset
- diarrhoea
- paraesthesia
- vertigo
- headache
- dizziness
- leucopaenia
- eosinophilia
- rash and pruritus
- Aspirin Gastric erosion
- ulceration and bleeding
- severe, occasionally fatal exacerbation of airway obstruction in asthma
- Reye's syndrome (childn Less than 12 yrs)
- Hepatotoxicity
- CNS depression, which may lead to coma
- CV collapse
- Respiratory failure
- paroxysmal bronchospasm and dyspnoea
- Clopidogrel Bleeding disorders including GI intracranial haemorrhage and thrombotic thrombocytopenic purpura
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac)
|
May increase the risk of stomach and intestinal bleeding
|
|
Coumarins, Anagrelide, Agatroban, LMWH, Bivalirudin, Dasatinib, Iloprost, Lepirudin, Tenecteplase
|
May increase the risk of bleeding
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Gout
|
Can worsen gout symptoms
|
|
Active Peptic Ulcer
|
Can worsen ulcer and increase bleeding risk
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a cool & dry place (below 30o C), protected from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.