Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Idiopathic Pulmonary Fibrosis
Condition: Initial dose titration
Dose: Capsule – 267 mg (1 capsule)
Frequency: three times daily by mouth
Duration: Days 1-7
Indication: Idiopathic Pulmonary Fibrosis
Condition: Initial dose titration
Dose: Capsule – 534 mg (2 capsules)
Frequency: three times daily by mouth
Duration: Days 8-14

Child Dose

Clinical InformationAdministration Information
Age: Child
Dose: Safety and efficacy not established
Note: Not recommended

Renal Dose

Clinical InformationAdministration Information
Condition: Mild, moderate, or severe renal impairment
Dose: Not specified
Note: Use caution; monitor and consider dosage modification or discontinuation as needed
Condition: End-stage renal disease requiring dialysis
Dose: Not specified
Note: No recommended (not studied)
Administration
  • Take with food
  • Take at same time each day
Side Effect

Drug Interaction

Drug NameRisk Factors
Grapefruit juice
Inhibition of CYP1A2
Fluvoxamine, other strong & selective CYP1A2 inhibitors, ciprofloxacin, amiodarone, propafenone
Increased exposure

Disease Interaction

Disease NameRisk Factors
Severe Hepatic Impairment
Risk of liver complications
End Stage Renal Disease
Risk of drug accumulation

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protected from light.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.