Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is a combination of two antiretroviral medications used to treat HIV infection. One component interferes with viral DNA production, while the other inactivates a crucial viral enzyme.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Tablets: Take with food • Oral suspension: Take with meal or nutritional supplement • Injection: Give over 90 minutes

Question 3

When should this medicine not be used?

Accepted Answer

• In heart rhythm problems • In severe liver disease • During pregnancy • When taking ergot medicines

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Use carefully in patients with heart rhythm problems • Use carefully in patients with liver problems • Avoid use during pregnancy and breastfeeding • May affect ability to drive • Monitor liver and kidney function, electrolyte levels, blood counts, and for fungal infections

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• May cause fetal harm based on animal studies • Insufficient human data to evaluate risk • Use only if potential benefit justifies the potential risk to the fetus

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Use carefully in patients with heart rhythm problems • Use carefully in patients with liver problems • Avoid use during pregnancy and breastfeeding • May affect ability to drive • Monitor liver and kidney function, electrolyte levels, blood counts, and for fungal infections

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Not recommended for children under 13 years. • No dose adjustment needed for elderly patients.

Question 8

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • If taken with meals: Take the dose with your next meal. • For thrice-daily dosing: If more than 3 hours until your next dose, take the missed dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Symptoms: QT prolongation, hepatotoxicity. • Treatment: ECG monitoring, liver function tests.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Fever, diarrhea, nausea, low potassium, headache, stomach pain, blood disorders • What to do: Take with food; Regular blood tests; Report severe symptoms; Monitor heart rhythm; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is Posanox 100mg used for?

Accepted Answer

Posanox 100mg (Posaconazole) is a pharmaceutical medicine manufactured by Opsonin Pharma Limited in Bangladesh. It is primarily prescribed for Candidemia, Oropharyngeal Candidiasis, Prophylaxis of Invasive Aspergillus.

Question 12

What is the active generic component of Posanox?

Accepted Answer

The active ingredient in Posanox is Posaconazole, belonging to the Drugs For Subcutaneous And Systemic Mycoses drug class.

Question 13

What is the retail price of Posanox 100mg in Bangladesh?

Accepted Answer

The official retail price of Posanox 100mg (Tablet) is ৳200.00 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 14

What is the recommended dosage for Posanox?

Accepted Answer

Standard adult dosage: Delayed-release tablet – 300 mg (twice daily on the 1st day, then once daily thereafter). Pediatric dosage: Intravenous – Dose not established. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 15

Is Posanox safe during pregnancy and breastfeeding?

Accepted Answer

Posanox is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 16

What are the common side effects of Posanox?

Accepted Answer

**More than 10%**; Fever (45%);Diarrhea (42%);Nausea (38%);Hypokalemia (30%);Headache (28%);Abd pain (27%);Anemia (25%);Cough (24%);Nausea (38%);Thrombocytopenia (29%);Constipation (21%);Dyspnea (20%);Febrile neutropenia

Clinical Information	Administration Information
Indication: Prophylaxis of invasive fungal infections Age: Adult	Dose: Delayed-release tablet – 300 mg Frequency: twice daily on the 1st day, then once daily thereafter Note: Treatment duration is based on recovery from neutropenia or immunosuppression
Indication: Prophylaxis of invasive fungal infections Age: Adult	Dose: Oral suspension – 200 mg Frequency: three times daily Note: Treatment duration is based on recovery from neutropenia or immunosuppression

Clinical Information	Administration Information
Indication: Invasive Aspergillus and Candida Infections Age: less than 18 years Condition: severely immunocompromised	Dose: Intravenous – Dose not established Note: Safety and efficacy not established
Indication: Invasive Aspergillus and Candida Infections Age: less than 13 years Condition: severely immunocompromised	Dose: Tablet and Oral suspension – Dose not established Note: Safety and efficacy not established

Clinical Information	Administration Information
Condition: Moderate-to-severe renal impairment (estimated glomerular filtration rate less than 50 mL/min)	Dose: Intravenous – Dose not specified Note: Avoid intravenous administration unless benefit/risk assessment justifies use. Accumulation of the intravenous vehicle, SBECD, is expected to occur. Serum creatinine levels should be closely monitored; if increases occur, consideration should be given to changing to oral posaconazole therapy.
Condition: Severe renal impairment	Dose: Tablets or Oral suspension – Dose not specified Note: Variability of systemic exposure with tablets or oral suspension observed. Monitored closely for breakthrough fungal infections.

Drug Name	Risk Factors
Efavirenz, fosamprenavir, cimetidine, esomeprazole, metoclopramide, phenytoin, rifabutin	Decreased plasma concentrations
Ritonavir, atazanavir	May increase plasma concentration

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Renal Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources