Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is a liver medication. It's used to treat primary biliary cholangitis. It works by regulating bile production and flow, helping to reduce liver damage.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Can be taken with or without food • Take at regular intervals • Separate from bile acid binding resins by 4 hours

Question 3

When should this medicine not be used?

Accepted Answer

• In severe liver disease • In bile duct blockage • During pregnancy

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Can cause liver problems • May cause severe itching • Can lower good cholesterol

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Use only if potential benefit outweighs potential risk • Limited data available on use during pregnancy • Consult doctor before use

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Can cause liver problems • May cause severe itching • Can lower good cholesterol

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Not established in children under 18 • No adjustment needed for elderly • For moderate/severe liver problems: - Start with 5mg weekly - Can increase based on response

Question 8

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For once-daily dosing: If you remember on the same day, take the dose. • Take your next dose at the regular time. • If you miss multiple doses, contact your doctor.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Severe pruritus, liver enzyme elevation. • Treatment: Stop drug, monitor liver function.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Itching, tiredness, stomach pain, joint pain, changes in cholesterol levels • What to do: Regular liver testing, report severe itching, maintain low-fat diet; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is Ocaliva 10mg used for?

Accepted Answer

Ocaliva 10mg (Obeticholic Acid) is a pharmaceutical medicine manufactured by Bio Pharma Laboratories Ltd. in Bangladesh. It is primarily prescribed for In Combination with Ursodeoxycholic Acid (UDCA) in Adults with An Inadequate Response to Udca for at Least 1 Yr, Monotherapy in Adults Unable to Tolerate Udca, Primary Biliary Cholangitis.

Question 12

What is the active generic component of Ocaliva?

Accepted Answer

The active ingredient in Ocaliva is Obeticholic Acid.

Question 13

What is the retail price of Ocaliva 10mg in Bangladesh?

Accepted Answer

The official retail price of Ocaliva 10mg (Tablet) is ৳55.00 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 14

What is the recommended dosage for Ocaliva?

Accepted Answer

Standard adult dosage: Tablet – 5 mg (by mouth once daily). Pediatric dosage: No approved pediatric dosage available. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 15

Is Ocaliva safe during pregnancy and breastfeeding?

Accepted Answer

Ocaliva is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 16

What are the common side effects of Ocaliva?

Accepted Answer

**More than 10%**; Pruritus (56-70%);Fatigue (19-25%);Severe pruritus (19-23%);Reduced HDL-C (9-20%);Abdominal pain and discomfort (10-19%); **1-10%**; Rash (7-10%);Oropharyngeal pain (7-8%);Dizziness (7%);Constipation (

Clinical Information	Administration Information
Indication: Primary Biliary Cholangitis Age: Adults Condition: Noncirrhotic or compensated Child-Pugh class A	Dose: Tablet – 5 mg Frequency: by mouth once daily Note: Starting dose. Before initiating, determine patient’s Child-Pugh classification (A, B, or C) using nomogram. Indicated in combination with ursodeoxycholic acid in adults with an inadequate response for at least 1 year or as monotherapy in adults unable to tolerate ursodeoxycholic acid.
Indication: Primary Biliary Cholangitis Age: Adults Condition: Noncirrhotic or compensated Child-Pugh class A (titration)	Dose: Tablet – 10 mg Frequency: once daily Note: If an adequate response has not been achieved after 3 months at 5 mg/day, and obeticholic acid is being tolerated, increase dose. Not to exceed 10 mg/day.

Drug Name	Risk Factors
Bile-acid binding resins	May reduce absorption, systemic exposure, and efficacy of obeticholic acid
Warfarin	May decrease INR; monitor INR and adjust warfarin dose accordingly

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources