Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Asymptomatic bacteriuria, Treatment and prophylaxis of chronic, uncomplicated lower urinary-tract infections Age: Adult Condition: As methenamine hippurate |
Dose: Oral – 1,000 mg Frequency: twice daily |
|
Indication: Asymptomatic bacteriuria, Treatment and prophylaxis of chronic, uncomplicated lower urinary-tract infections Age: Adult Condition: In catheterised patient, As methenamine hippurate |
Dose: Oral – 1,000 mg Frequency: three times daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Asymptomatic bacteriuria, Treatment and prophylaxis of chronic, uncomplicated lower urinary-tract infections Age: less than 6 years |
Dose: Oral methenamine mandelate – 18 mg/kg Frequency: 4 times daily |
|
Indication: Asymptomatic bacteriuria, Treatment and prophylaxis of chronic, uncomplicated lower urinary-tract infections Age: 6-12 years |
Dose: Oral methenamine hippurate – 500-1,000 mg Frequency: twice daily |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Form – Not specified Note: Renal impairment: Contraindicated. |
Administration
- Take with plenty of water
- Take at regular intervals
Side Effect
- Dysuria
- Gastric upset
- Nausea
- Rash
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Acetazolamide
|
May inhibit conversion of methenamine into formaldehyde
|
|
Sulfonamides (e.g. sulfamethizole)
|
Risk of crystalluria
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Gout
|
Can worsen uric acid levels
|
|
Metabolic Acidosis
|
Can increase blood acidity
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.