Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Active Tuberculosis Disease
Age: Adult
Dose: Oral – 5 mg/kg
Frequency: once daily
Note: not to exceed 300 mg once daily; used in multi-drug regimen containing rifampin (or ribabutin or rifapentin), pyrazinamide, and ethambutol
Indication: Active Tuberculosis Disease
Age: Adult
Dose: Oral – 15 mg/kg
Frequency: 1-3 times/week
Note: not to exceed 900 mg; used in multi-drug regimen containing rifampin (or ribabutin or rifapentin), pyrazinamide, and ethambutol

Child Dose

Clinical InformationAdministration Information
Indication: Active Tuberculosis Disease
Dose: Oral – 10-15 mg/kg
Frequency: once daily
Note: not to exceed 300 mg/day; used in multi-drug regimen
Indication: Active Tuberculosis Disease
Dose: Oral – 20-30 mg/kg
Frequency: 2 times/week
Note: up to 900 mg; used in multi-drug regimen

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment: Severe
Dose: Not mentioned
Note: Dose reduction may be needed
Administration
  • Take on empty stomach
  • 1hr before/2hrs after food
Side Effect

Drug Interaction

Drug NameRisk Factors
Carbamazepine, Ethosuximide, Primidone, Phenytoin, Diazepam, Triazolam, Chlorzoxazone, Theophylline, Disulfiram
Inhibit the hepatic metabolism
Enflurane
Increased metabolism resulting in potentially nephrotoxic levels of fluoride

Disease Interaction

Disease NameRisk Factors
Acute Liver Disease, Previous INH-induced hepatitis
Can cause severe liver damage
Acute Liver Disease
Can cause severe liver damage

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage

Details coming soon

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.