Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Psychoses, Schizophrenia Age: Adult Condition: Outpatient |
Dose: Oral – 1-2 mg Frequency: every 12 hours |
|
Indication: Psychoses, Schizophrenia Age: Adult Condition: Inpatient Initial |
Dose: Oral – 2-5 mg Frequency: every 12 hours |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Schizophrenia/Psychosis Age: less than 6 years Condition: Inpatient |
Dose: PO – Not established Note: Safety and efficacy not established |
|
Indication: Schizophrenia/Psychosis Age: 6-12 years old Condition: Inpatient |
Dose: PO – 1 mg Frequency: once daily or every 12 hours Note: by mouth (oral); not to exceed 15 mg/day |
Administration
- Should be taken with food
- Take at the same time each day
Side Effect
- EPS (60%, muscle stiffness, dystonia, parkinsonism, tardive dyskinesia, akathisia)
- Drowsiness
- dry mouth
- blurred vision
- dizziness
- sedation
- antimuscarinic affects
- postural hypotension
- akathisia
- muscle weakness
- anorexia
- insomnia
- rash
- amenorrhoea
- fatigue
- increased prolactin levels
- Neuroleptic malignant syndrome
- blood dyscrasias
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
CNS depressants (opiates, other analgesics, barbiturates, sedatives, general anaesthetics, alcohol)
|
Increased CNS depression
|
|
Drugs with antimuscarinic properties (e.g. TCA, antiparkinsonian drugs)
|
Increased risk of side effects
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
CNS Depression/Coma
|
Can worsen brain function
|
|
Blood Dyscrasias/Liver Disease
|
Can worsen condition
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
It should be store at room temperature between 15-30° C away from light and moisture.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.