Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Advanced Prostate Cancer Age: Adult Condition: Day 1 Loading Dose |
Dose: PO – 360 mg Frequency: once Note: by mouth |
|
Indication: Advanced Prostate Cancer Age: Adult Condition: Maintenance Dose |
Dose: PO – 120 mg Frequency: once daily Note: by mouth |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Mild-to-severe renal impairment (Creatinine Clearance 15-89 mL/minute) |
Dose: Not specified Note: No dosage adjustment required |
|
Condition: End-stage renal disease with or without hemodialysis |
Dose: Not specified Note: Not studied |
Administration
- Take at approximately same time each day
- May take with or without food
Side Effect
- Hot flush (54%)
- Glucose increased (44%)
- Triglycerides increased (35%)
- Musculoskeletal pain (30%)
- Hemoglobin decreased (28%)
- ALT increased (27%)
- Fatigue (26%)
- AST increased (18%)
- Diarrhea (12%)
- Constipation (12%)
- Increased weight (Less than 10%)
- Insomnia (Less than 10%)
- Gynecomastia (Less than 10%)
- Hyperhidrosis (Less than 10%)
- Depression (Less than 10%)
- Decreased libido (Less than 10%)
- Glucose increased (2.9%)
- Triglycerides increased (2%)
- Musculoskeletal pain (1.1%)
- Hot flush
- Fatigue
- Diarrhea
- ALT increased
- Hemoglobin increased
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
No interactions listed
|
-
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.