Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Postmenopausal osteoporosis Age: Adult |
Dose: Capsule – 0.25 mcg Frequency: twice daily Note: Serum creatinine levels should be determined at 4 weeks, 3 and 6 months and 6 monthly intervals thereafter. |
|
Indication: Postmenopausal osteoporosis Age: Adult |
Dose: Capsule – 0.50 mcg Frequency: once daily Note: Serum creatinine levels should be determined at 4 weeks, 3 and 6 months and 6 monthly intervals thereafter. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Chronic Renal Dialysis Associated Hypocalcemia |
Dose: Oral – 0.25-2 mcg/day Frequency: once daily Note: by mouth (oral) |
|
Indication: Hypoparathyroidism/Pseudohypoparathyroidism Age: less than 1 year |
Dose: Oral – 0.04-0.08 mcg/kg Frequency: once daily Note: by mouth (oral) |
Administration
- Can be taken with or without food
- Take with water
Side Effect
- Abdominal pain
- Apathy
- BUN and creatinine increased
- Cardiac arrhythmia
- Constipation
- Dry mouth
- Dehydration
- Growth suppression
- Headache
- Hyperthermia
- Hypercalcemia
- Hypercholesteremia
- Hypermagnesemia
- Hyperphosphatemia
- Hypertension
- Libido decreased
- Metallic taste
- Muscle or bone pain
- Nocturia
- Pruritus
- Psychosis
- Somnolence
- Weakness
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Magnesium-containing drugs
|
Hypermagnesaemia may develop in patients on chronic renal dialysis
|
|
Digitalis
|
Hypercalcaemia in patients on digitalis may precipitate cardiac arrhythmias
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypercalcaemia, Evidence of Vitamin D Toxicity
|
Can worsen calcium levels
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
keep in a dry place away from light and heat. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.