Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Diabetes Mellitus Age: Adult Condition: Combination rapid-onset and intermediate-acting insulins (30% soluble insulin aspart and 70% protamine-crystallised insulin aspart) |
Dose: Subcutaneous Injection – 0.5-1 unit/kg Frequency: every 12 hours (before breakfast and evening meal) Note: Dose regimen varies among patients depending on metabolic needs; each dose intended to cover 2 meals or a meal and snack. |
|
Indication: Diabetes Mellitus Age: Adult Condition: Insulin naive patients with Type 2 Diabetes |
Dose: Subcutaneous Injection – 6 Units Frequency: twice daily (at breakfast and dinner) Note: Recommended starting dose. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Safety and efficacy not established Note: Not recommended |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Dose adjustments may be needed. Note: Renal impairment: Dose adjustments may be needed. |
Administration
- Inject subcutaneously
- Rotate between upper arm, thigh, abdomen
Side Effect
- Hypoglycemia (47-69%)
- Headache (12-35%)
- Influenza-like symptoms (12-13%)
- Headache (9%)
- Dyspepsia (9%)
- Diarrhea (7-8%)
- Back pain (7%)
- Pharyngitis (6-7%)
- Insulin resistance
- Lipodystrophy
- Lipohypertrophy
- Local allergic reaction
- Hypokalemia
- Weight gain
- Peripheral edema
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Oral hypoglycemics, octreotide, MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide), nonselective β-adrenergic blockers, ACE Inhibitors (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril), salicylates, alcohol, anabolic steroids, sulfonamides
|
Reduce insulin requirements
|
|
OCs, thiazides, glucocorticoids, thyroid hormones, Sympathomimetics (Ephedrine, Pseudoephedrine, Phenylephrine), danazol
|
Increase insulin requirements
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypoglycemia
|
Risk of dangerously low blood sugar
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.