Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Prevention of Chemotherapy-induced Nausea and Vomiting
Age: Adult
Dose: Intravenous – 0.25 mg
Frequency: single dose
Note: To be given over 30 seconds and 30 minutes before chemotherapy. Do not repeat within 7 days. Hepatic impairment: Dose adjustment not necessary.
Indication: Prevention of Chemotherapy-induced Nausea and Vomiting
Age: Adult
Dose: Tablet/capsule – 0.5 mg
Frequency: approximately 1 hour before the start of chemotherapy, then once daily
Note: Hepatic impairment: Dose adjustment not necessary.

Child Dose

Clinical InformationAdministration Information
Indication: Prevention of Postoperative Nausea and Vomiting
Age: less than 18 years
Dose: Not established
Note: Safety and efficacy not established
Indication: Prevention of Chemotherapy-induced Nausea and Vomiting
Age: less than 1 month
Dose: Not established
Note: Safety and efficacy not established

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Dose adjustment not necessary
Note: Renal impairment: Dose adjustment not necessary
Administration
  • Mix with approved solutions (5% glucose, 0.9% saline, or lactated Ringer's with 5% glucose)
  • Before use: Clean IV line with normal saline
Side Effect

Drug Interaction

Drug NameRisk Factors
Moxifloxacin, Erythromycin, Antipsychotics (Haloperidol, Risperidone, Quetiapine, Olanzapine, Clozapine, Aripiprazole), TCAs
May have additive effect on prolonging QT

Disease Interaction

Disease NameRisk Factors
No specific contraindications listed
Monitor for general reactions

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool & dry place, protected from light.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.