Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Moderate to severe acute pain
Age: Adult
Dose: Oral – Initially, 50 mg, 75 mg or 100 mg
Frequency: every 4-6 hours
Note: Initial dose depends on pain intensity. On day 1, a 2nd dose may be given 1 hour after the initial dose if pain relief is inadequate; subsequent doses may be given every 4-6 hours, adjusted according to response. Maximum dose: 700 mg on day 1, 600 mg daily on subsequent days.
Indication: Moderate to severe acute pain
Age: Elderly
Dose: Oral – Initiate dosage at lower end of range
Note: Initially, 50 mg, 75 mg or 100 mg every 4-6 hours, depending on pain intensity. Maximum dose: 700 mg on day 1, 600 mg daily on subsequent days.

Child Dose

Clinical InformationAdministration Information
Age: Child
Dose: Safety and efficacy not established
Note: Safety and efficacy not established

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Not specified
Note: Dosage adjustment not required
Condition: Renal impairment
Dose: Not specified
Note: Not recommended
Administration
  • Can be taken with or without food
  • Take at regular intervals
Side Effect

Drug Interaction

Drug NameRisk Factors
MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide)
Potential severe adverse effects
CNS-active drugs, Serotonergic agents
Increased risk of adverse effects

Disease Interaction

Disease NameRisk Factors
Significant Respiratory Depression
Can cause breathing problems
Severe Bronchial Asthma/Hypercapnia
Risk of respiratory failure

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protected from light and moisture. Keep the medicine out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.