Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Acute uncomplicated urinary tract infections
Age: Adult
Dose: Oral – 50-100 mg
Frequency: four times daily
Duration: 7 days or for 3 days after obtaining sterile urine
Indication: Acute uncomplicated urinary tract infections
Age: Adult
Condition: SR preparation
Dose: Oral – 100 mg
Frequency: twice daily
Duration: 7 days or for 3 days after obtaining sterile urine

Child Dose

Clinical InformationAdministration Information
Indication: Urinary Tract Infection
Age: greater than 1 month
Dose: by mouth (oral) – 5-7 mg/kg/day
Frequency: divided every 6 hours
Duration: for 7 days
Indication: UTI prophylaxis
Age: greater than 1 month
Dose: by mouth (oral) – 1-2 mg/kg
Frequency: at bedtime or 2 divided doses

Renal Dose

Clinical InformationAdministration Information
Condition: creatinine clearance less than 60 mL/min
Dose: Not specified
Note: Loses effectiveness in patients with creatinine clearance less than 60 mL/min due to inadequate urine concentration
Age: Geriatric
Condition: Decreased renal function
Dose: Not specified
Note: Monitor renal function; renally excreted; decreased renal function more likely in elderly
Administration
  • Take with food or milk
  • Take at same times each day
Side Effect

Drug Interaction

Drug NameRisk Factors
Probenecid, Sulfinpyrazone
Reduced excretion
Magnesium trisilicate
Absorption reduced

Disease Interaction

Disease NameRisk Factors
Severe Renal Impairment
Drug accumulation can cause toxicity
Anuria
Medication will be ineffective

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Do not store above 30°C. Keep away from light and out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.