Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Passive immunisation against hepatitis B infection
Age: Adult
Dose: Intramuscular – 500 IU
Frequency: single dose
Note: Given preferably within 48 hours of exposure and not greater than 1 week after exposure. Contents of hepatitis B immunoglobulin may vary between countries and between manufacturers. Caution should be taken in interpreting dosage recommendations which are not given in terms of IU.
Indication: Prophylaxis of hepatitis B recurrence after liver transplantation
Age: Adult
Dose: Intravenous – 20,000 IU/dose
Frequency: 1 dose
Duration: with liver transplant
Note: Initially given. Contents of hepatitis B immunoglobulin may vary between countries and between manufacturers. Caution should be taken in interpreting dosage recommendations which are not given in terms of IU.

Child Dose

Clinical InformationAdministration Information
Indication: Passive immunisation against hepatitis B infection
Age: less than 5 years
Dose: Intramuscular – 200 IU
Frequency: single dose
Note: preferably within 48 hours of exposure and not greater than 1 week after exposure; contents of hepatitis B immunoglobulin may vary between countries and between manufacturers
Indication: Passive immunisation against hepatitis B infection
Age: 5-9 years
Dose: Intramuscular – 300 IU
Frequency: single dose
Note: preferably within 48 hours of exposure and not greater than 1 week after exposure; contents of hepatitis B immunoglobulin may vary between countries and between manufacturers
Administration
  • For IM use only
  • Must be given by healthcare professional
Side Effect

Drug Interaction

Drug NameRisk Factors
Live vaccines
May interfere with immune response

Disease Interaction

Disease NameRisk Factors
Severe Gamma Globulin Allergy
Risk of life-threatening reaction
Thrombocytopenia
Risk with intramuscular injection

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a refrigerator (2-8°C). Keep in the outer carton in order to protect from light. Keep out of the reach and sight of children

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.